PDF(Pubmed)
Abstract：
Erythema nodosum (EN) is the most common form of panniculitis and occurs in about one in 100,000 people. EN typically presents as an eruption of tender, erythematous nodules on the anterior aspect of the legs, although the face, trunk, and arms can also be involved. While the majority of cases are idiopathic, a subset of cases occurs in association with various triggers, including infections, medications, tumors, and autoimmune diseases. Rarely can EN develop in relation to pregnancy, which is thought to provide a physiologic background that favors its development. While pregnancy has been associated with EN in a minority of cases, currently, there is a limited amount of data suggesting that EN can develop in the late postpartum period. Herein, we present a case of a 20-year-old female with a six-week history of painful lesions on her lower extremities. A physical exam revealed multiple tender, erythematous nodules on the anterior aspect of the lower extremities, spanning from the knees to the toes. Laboratory workup showed no other identified triggers of EN in our patient besides pregnancy. Management of EN in our patient involved a low dose, six-day course of prednisone (initial dose of 15 mg/day) and ibuprofen for one week, leading to symptomatic improvement. Our case emphasizes the possibility of EN presenting in the late postpartum period. This case underscores the importance of considering EN in the differential diagnoses for women presenting with compatible lesions postpartum.
摘要：
结节性红斑（EN）是最常见的脂膜炎形式，约发生在100,000人中。EN通常表现为招标的爆发，腿前部的红斑结节，虽然脸,树干,武器也可以参与其中。虽然大多数病例是特发性的，案件的子集与各种触发因素相关联，包括感染,药物,肿瘤，和自身免疫性疾病。很少能与怀孕有关的EN发展，这被认为提供了有利于其发展的生理背景。虽然在少数病例中怀孕与EN有关，目前,有限的数据表明EN可以在产后后期发展。在这里，我们介绍一例20岁女性,有6周下肢疼痛性病变史.体格检查显示多重招标，下肢前部的红斑结节，从膝盖到脚趾。实验室检查显示，除了怀孕外，我们的患者没有其他确定的EN触发因素。我们患者的EN管理涉及低剂量，强的松（初始剂量为15毫克/天）和布洛芬为期一周的六天疗程，导致症状改善。我们的案例强调了在产后后期出现EN的可能性。此病例强调了在产后出现相容性病变的妇女的鉴别诊断中考虑EN的重要性。
