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Abstract：
UNASSIGNED: Osteoporotic vertebral compression fractures (OVCF) appear to be more common as the population ages. Previous studies have found that percutaneous vertebroplasty (PVP) can achieve better short-term clinical outcomes than conservative treatment (CT) for OVCF. However, the long-term outcomes of PVP compared with CT for OVCF has been rare explored. This study was designed to explore the clinical outcomes of PVP or CT within 3 years after OVCF.
UNASSIGNED: This study reviewed the clinical outcomes of patients who underwent PVP or CT for OVCF in a single center from January 2015 to December 2019. The back pain visual analogue scale (VAS), Oswestry disability index (ODI) and satisfaction rate were compared between the two groups at baseline, 1 week, 1 month, 3 months, 6 months, 12 months, 24 months and 36 months after treatment.
UNASSIGNED: The baseline data including gender, age, bone mineral density, body mass index, back pain VAS, and ODI were not significantly different between the two groups. The back pain VAS and ODI of CT patients were significantly higher than those of PVP group at 1 week, 1 month, 3 months, 6 months and 12 months after treatment. The satisfaction rate in the PVP group were significantly higher than those in the CT group at 1 week, 1 month, 3 months and 6 months after treatment. Subsequently, the back pain VAS and ODI showed no significant difference between the two groups at 24 and 36 months. In addition, there was no significant difference in treatment satisfaction between the two groups at 36 months. There was no significant difference in the rate of new vertebral compression fractures between the two groups within 36 months after treatment.
UNASSIGNED: The clinical outcomes within 12 months after PVP and patient satisfaction rate within 6 months after PVP were significantly higher than CT. However, during 12 months to 36 months, this advantage generated by PVP was gradually diluted over time. Compared with CT, the long-term effect of PVP on OVCF should not be overestimated.
UNASSIGNED: This study reviewed the clinical outcomes of patients who underwent PVP or CT for OVCF in a single center from January 2015 to December 2019. The back pain visual analogue scale (VAS), Oswestry disability index (ODI) and satisfaction rate were compared between the two groups at baseline, 1 week, 1 month, 3 months, 6 months, 12 months, 24 months and 36 months after treatment.
UNASSIGNED: The baseline data including gender, age, bone mineral density, body mass index, back pain VAS, and ODI were not significantly different between the two groups. The back pain VAS and ODI of CT patients were significantly higher than those of PVP group at 1 week, 1 month, 3 months, 6 months and 12 months after treatment. The satisfaction rate in the PVP group were significantly higher than those in the CT group at 1 week, 1 month, 3 months and 6 months after treatment. Subsequently, the back pain VAS and ODI showed no significant difference between the two groups at 24 and 36 months. In addition, there was no significant difference in treatment satisfaction between the two groups at 36 months. There was no significant difference in the rate of new vertebral compression fractures between the two groups within 36 months after treatment.
UNASSIGNED: The clinical outcomes within 12 months after PVP and patient satisfaction rate within 6 months after PVP were significantly higher than CT. However, during 12 months to 36 months, this advantage generated by PVP was gradually diluted over time. Compared with CT, the long-term effect of PVP on OVCF should not be overestimated.
摘要：
■骨质疏松性椎体压缩性骨折（OVCF）似乎随着人口的老龄化而更加常见。先前的研究发现，经皮椎体成形术（PVP）可以比保守治疗（CT）获得更好的短期临床疗效。然而,PVP与CT治疗OVCF的长期结局比较少见.本研究旨在探讨OVCF后3年内PVP或CT的临床结果。
■本研究回顾了2015年1月至2019年12月在单中心接受PVP或CT治疗OVCF的患者的临床结果。背痛视觉模拟量表（VAS），比较两组患者基线时Oswestry残疾指数(ODI)和满意率,1周,1个月,3个月,6个月,12个月,治疗后24个月和36个月。
■基线数据包括性别，年龄,骨矿物质密度，身体质量指数,背痛VAS,和ODI在两组之间没有显着差异。1周时CT组患者的背痛VAS和ODI明显高于PVP组,1个月,3个月,治疗后6个月和12个月。1周时PVP组的满意率明显高于CT组,1个月,治疗后3个月和6个月。随后，在24个月和36个月时,两组的背痛VAS和ODI无显著差异.此外,在36个月时,两组患者的治疗满意度无显著差异.两组患者治疗后36个月内新发椎体压缩性骨折的发生率差异无统计学意义。
■PVP术后12个月内的临床结局和PVP术后6个月内的患者满意率明显高于CT。然而,在12个月至36个月期间，PVP产生的这种优势随着时间的推移逐渐被稀释.与CT相比,PVP对OVCF的长期影响不应高估。
■本研究回顾了2015年1月至2019年12月在单中心接受PVP或CT治疗OVCF的患者的临床结果。背痛视觉模拟量表（VAS），比较两组患者基线时Oswestry残疾指数(ODI)和满意率,1周,1个月,3个月,6个月,12个月,治疗后24个月和36个月。
■基线数据包括性别，年龄,骨矿物质密度，身体质量指数,背痛VAS,和ODI在两组之间没有显着差异。1周时CT组患者的背痛VAS和ODI明显高于PVP组,1个月,3个月,治疗后6个月和12个月。1周时PVP组的满意率明显高于CT组,1个月,治疗后3个月和6个月。随后，在24个月和36个月时,两组的背痛VAS和ODI无显著差异.此外,在36个月时,两组患者的治疗满意度无显著差异.两组患者治疗后36个月内新发椎体压缩性骨折的发生率差异无统计学意义。
■PVP术后12个月内的临床结局和PVP术后6个月内的患者满意率明显高于CT。然而,在12个月至36个月期间，PVP产生的这种优势随着时间的推移逐渐被稀释.与CT相比,PVP对OVCF的长期影响不应高估。
