PDF(Pubmed)
Abstract：
BACKGROUND: Recent reviews have outlined the main nanomaterials used in relation to gastrointestinal tumors and described the basic properties of these materials. However, the research hotspots and trends in the application of nanomaterials in gastric cancer (GC) remain obscure.
OBJECTIVE: To demonstrate the knowledge structure and evolutionary trends of research into the application of nanomaterials in GC.
METHODS: Publications related to the application of nanomaterials in GC were retrieved from the Web of Science Core Collection for this systematic review and bibliometric study. VOSviewer and CiteSpace were used for bibliometric and visualization analyses.
RESULTS: From 2000 to 2022, the application of nanomaterials in GC developed rapidly. The keyword co-occurrence analysis showed that the related research topics were divided into three clusters: (1) The application of nanomaterials in GC treatment; (2) The application and toxicity of nanomaterials in GC diagnosis; and (3) The effects of nanomaterials on the biological behavior of GC cells. Complexes, silver nanoparticles, and green synthesis are the latest high-frequency keywords that represent promising future research directions.
CONCLUSIONS: The application of nanomaterials in GC diagnosis and treatment and the mechanisms of their effects on GC cells have been major themes in this field over the past 23 years.
OBJECTIVE: To demonstrate the knowledge structure and evolutionary trends of research into the application of nanomaterials in GC.
METHODS: Publications related to the application of nanomaterials in GC were retrieved from the Web of Science Core Collection for this systematic review and bibliometric study. VOSviewer and CiteSpace were used for bibliometric and visualization analyses.
RESULTS: From 2000 to 2022, the application of nanomaterials in GC developed rapidly. The keyword co-occurrence analysis showed that the related research topics were divided into three clusters: (1) The application of nanomaterials in GC treatment; (2) The application and toxicity of nanomaterials in GC diagnosis; and (3) The effects of nanomaterials on the biological behavior of GC cells. Complexes, silver nanoparticles, and green synthesis are the latest high-frequency keywords that represent promising future research directions.
CONCLUSIONS: The application of nanomaterials in GC diagnosis and treatment and the mechanisms of their effects on GC cells have been major themes in this field over the past 23 years.
摘要：
背景：最近的综述概述了与胃肠道肿瘤有关的主要纳米材料，并描述了这些材料的基本特性。然而,纳米材料在胃癌中的应用研究热点和趋势尚不清楚。
目的：展示纳米材料在GC中的应用研究的知识结构和演化趋势。
方法：从WebofScienceCoreCollection检索到与纳米材料在GC中的应用有关的出版物，用于本系统综述和文献计量学研究。VOSviewer和CiteSpace用于文献计量和可视化分析。
结果：从2000年到2022年，纳米材料在GC中的应用发展迅速。关键词共现分析表明,相关研究课题分为三个簇:(1)纳米材料在GC处理中的应用;(2)纳米材料在GC诊断中的应用及毒性;(3)纳米材料对GC细胞生物学行为的影响。复合物，银纳米粒子，和绿色合成是最新的高频关键词，代表了有希望的未来研究方向。
结论：纳米材料在GC诊断和治疗中的应用及其对GC细胞的作用机制是近23年来研究该领域的主要课题。
目的：展示纳米材料在GC中的应用研究的知识结构和演化趋势。
方法：从WebofScienceCoreCollection检索到与纳米材料在GC中的应用有关的出版物，用于本系统综述和文献计量学研究。VOSviewer和CiteSpace用于文献计量和可视化分析。
结果：从2000年到2022年，纳米材料在GC中的应用发展迅速。关键词共现分析表明,相关研究课题分为三个簇:(1)纳米材料在GC处理中的应用;(2)纳米材料在GC诊断中的应用及毒性;(3)纳米材料对GC细胞生物学行为的影响。复合物，银纳米粒子，和绿色合成是最新的高频关键词，代表了有希望的未来研究方向。
结论：纳米材料在GC诊断和治疗中的应用及其对GC细胞的作用机制是近23年来研究该领域的主要课题。
