PDF(Pubmed)
Abstract：
UNASSIGNED: To describe and compare a peritoneal closure technique using cyanoacrylate glue (Glubran 2®, GEM, Cardiolink SL) with a microdroplet device (Glutack®, GEM, Cardiolink SL) in laparoscopic transabdominal preperitoneal repair (TAPP) of inguinal hernia with the routinely used barbed suture peritoneal closure (V-Lock 3.0, Covidien France).
UNASSIGNED: From January to August 2022, 60 patients undergoing TAPP repair for uni- or bilateral inguinal hernia were randomized into one of two groups. One using as mesh fixation and peritoneal closure the Glutack® device with Glubran 2® cyanoacrylate glue (Glu-close group) and the other using mesh fixation with cyanoacrylate and peritoneal closure with V-lock 3.0 (Sut-close group), with a follow-up of 12 months. Demographic variables, operative time, peritoneal closure time, main surgical findings and main intra- and postoperative complications were analyzed prospectively.
UNASSIGNED: 63 patients were included with no losses to follow-up. The mean operative time was 34 min (range 58.25) for the glu-close group and 40 (range 64.25) for the sut-close group, with no conversion (0%) for either group. The mean flap closure time was 1.18 min (SD 24 0.19) for the glu-close group and 3.24 min (SD 0.78) for the sut-close group, with statistically significant differences (p < 0.001). The intraoperative complication rate was 0 for the glu-close group and 0 for the sut-close group, with no significant difference. The median hospital stay was 0.8 days (range, 0-1) for both groups. The median duration of follow-up was 12 months and none had hernia recurrence. The postoperative VAS score at the first and second check-up at 1 month and 3 months was 2.83 (SD 1.341) and 0.60 (SD 0.621) in the sut-close group and 1.03 (0.984) and 0.24 (SD 0.435) in the glue-close group, with significant differences (p < 0.001 and p < 0.012).
UNASSIGNED: The data demonstrated by the study are that the glue can be used safely to close the peritoneum and that the method provides a small, statistically significant but not clinically relevant reduction in the time to close the peritoneal flap, as well as in postoperative pain after surgery in short and medium term.
UNASSIGNED: From January to August 2022, 60 patients undergoing TAPP repair for uni- or bilateral inguinal hernia were randomized into one of two groups. One using as mesh fixation and peritoneal closure the Glutack® device with Glubran 2® cyanoacrylate glue (Glu-close group) and the other using mesh fixation with cyanoacrylate and peritoneal closure with V-lock 3.0 (Sut-close group), with a follow-up of 12 months. Demographic variables, operative time, peritoneal closure time, main surgical findings and main intra- and postoperative complications were analyzed prospectively.
UNASSIGNED: 63 patients were included with no losses to follow-up. The mean operative time was 34 min (range 58.25) for the glu-close group and 40 (range 64.25) for the sut-close group, with no conversion (0%) for either group. The mean flap closure time was 1.18 min (SD 24 0.19) for the glu-close group and 3.24 min (SD 0.78) for the sut-close group, with statistically significant differences (p < 0.001). The intraoperative complication rate was 0 for the glu-close group and 0 for the sut-close group, with no significant difference. The median hospital stay was 0.8 days (range, 0-1) for both groups. The median duration of follow-up was 12 months and none had hernia recurrence. The postoperative VAS score at the first and second check-up at 1 month and 3 months was 2.83 (SD 1.341) and 0.60 (SD 0.621) in the sut-close group and 1.03 (0.984) and 0.24 (SD 0.435) in the glue-close group, with significant differences (p < 0.001 and p < 0.012).
UNASSIGNED: The data demonstrated by the study are that the glue can be used safely to close the peritoneum and that the method provides a small, statistically significant but not clinically relevant reduction in the time to close the peritoneal flap, as well as in postoperative pain after surgery in short and medium term.
摘要：
■为了描述和比较使用氰基丙烯酸酯胶（Glubran2®，创业板,CardiolinkSL)与微滴装置(Glutack®,创业板,CardiolinkSL）用于腹股沟疝的腹腔镜经腹腹膜前修补术（TAPP），并常规使用倒刺缝合腹膜闭合（V-Lock3.0，CovidienFrance）。
■从2022年1月至8月，将60例接受TAPP修补术治疗单发或双侧腹股沟疝的患者随机分为两组。一种使用Glutack®装置与Glubran2®氰基丙烯酸酯胶(Glu-close组)作为网片固定和腹膜闭合,另一种使用氰基丙烯酸酯作为网片固定并使用V-lock3.0(Sut-close组)进行腹膜闭合,随访12个月。人口统计变量，手术时间,腹膜闭合时间,前瞻性分析主要手术表现和术中术后主要并发症。
■纳入63例患者，随访无损失。glu-close组的平均手术时间为34分钟（范围58.25），sut-close组的平均手术时间为40分钟（范围64.25）。两组均无转化(0%)。闭合组的平均皮瓣闭合时间为1.18分钟（SD240.19），闭合组的平均皮瓣闭合时间为3.24分钟（SD0.78），差异有统计学意义(p<0.001)。术中并发症发生率glu-close组为0，sut-close组为0，没有显著差异。中位住院时间为0.8天(范围，0-1）两组。中位随访时间为12个月，无疝气复发。术后1个月和3个月的第一次和第二次检查时的VAS评分，超接近组分别为2.83（SD1.341）和0.60（SD0.621），胶合组分别为1.03（0.984）和0.24（SD0.435），差异显著(p<0.001和p<0.012)。
■研究证明的数据是，可以安全地使用胶水来关闭腹膜，并且该方法提供了一个小的，腹膜瓣闭合时间的减少具有统计学意义，但没有临床相关性，以及术后中短期疼痛。
■从2022年1月至8月，将60例接受TAPP修补术治疗单发或双侧腹股沟疝的患者随机分为两组。一种使用Glutack®装置与Glubran2®氰基丙烯酸酯胶(Glu-close组)作为网片固定和腹膜闭合,另一种使用氰基丙烯酸酯作为网片固定并使用V-lock3.0(Sut-close组)进行腹膜闭合,随访12个月。人口统计变量，手术时间,腹膜闭合时间,前瞻性分析主要手术表现和术中术后主要并发症。
■纳入63例患者，随访无损失。glu-close组的平均手术时间为34分钟（范围58.25），sut-close组的平均手术时间为40分钟（范围64.25）。两组均无转化(0%)。闭合组的平均皮瓣闭合时间为1.18分钟（SD240.19），闭合组的平均皮瓣闭合时间为3.24分钟（SD0.78），差异有统计学意义(p<0.001)。术中并发症发生率glu-close组为0，sut-close组为0，没有显著差异。中位住院时间为0.8天(范围，0-1）两组。中位随访时间为12个月，无疝气复发。术后1个月和3个月的第一次和第二次检查时的VAS评分，超接近组分别为2.83（SD1.341）和0.60（SD0.621），胶合组分别为1.03（0.984）和0.24（SD0.435），差异显著(p<0.001和p<0.012)。
■研究证明的数据是，可以安全地使用胶水来关闭腹膜，并且该方法提供了一个小的，腹膜瓣闭合时间的减少具有统计学意义，但没有临床相关性，以及术后中短期疼痛。
