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Abstract：
BACKGROUND: Cough is a major complication after lung cancer surgery, potentially impacting lung function and quality of life. However, effective treatments for managing long-term persistent postoperative cough remain elusive. In this study, we investigated the potential of a pulmonary rehabilitation training program to effectively address this issue.
METHODS: Between January 2019 and December 2022, a retrospective review was conducted on patients with non-small cell lung cancer (NSCLC) who underwent lobectomy and lymph node dissection via video-assisted thoracoscopic surgery (VATS) at Daping hospital. Based on their postoperative rehabilitation methods, the patients were categorized into 2 groups: the traditional rehabilitation group and the pulmonary rehabilitation group. All patients underwent assessment using the Leicester cough questionnaire (LCQ) on the third postoperative day. Additionally, at the 6-month follow-up, patients\' LCQ scores and lung function were re-evaluated to assess the long-term effects of the pulmonary rehabilitation training programs.
RESULTS: Among the 276 patients meeting the inclusion criteria, 195 (70.7%) were in the traditional rehabilitation group, while 81 (29.3%) participated in the pulmonary rehabilitation group. The pulmonary rehabilitation group showed a significantly lower incidence of cough on the third postoperative day (16.0% vs 29.7%, P = .018) and higher LCQ scores in the somatic dimension (5.09 ± .81 vs 4.15 ± 1.22, P = .007) as well as in the total score (16.44 ± 2.86 vs 15.11 ± 2.51, P = .018, whereas there were no significant differences in psychiatric and sociological dimensions. At the 6-month follow-up, the pulmonary rehabilitation group continued to have a lower cough incidence (3.7% vs 12.8%, P = .022) and higher LCQ scores across all dimensions: somatic (6.19 ± .11 vs 5.75 ± 1.20, P = .035), mental (6.37 ± 1.19 vs 5.85 ± 1.22, P = .002), sociological (6.76 ± 1.22 vs 5.62 ± 1.08, P < .001), and total (18.22 ± 2.37 vs 16.21 ± 2.53, P < .001). Additionally, lung function parameters including FVC, FVC%, FEV1, FEV1%, MVV, MVV%, DLCO SB, and DLCO% were all significantly higher in the pulmonary rehabilitation group compared to the traditional group.
CONCLUSIONS: Pulmonary rehabilitation exercises significantly reduced the incidence of postoperative cough and improved cough-related quality of life in patients undergoing lobectomy, with sustained benefits observed at the 6-month follow-up. Additionally, these exercises demonstrated superior lung function outcomes compared to traditional rehabilitation methods.
Pulmonary rehabilitation exercises significantly reduced the incidence of postoperative cough and improved cough-related quality of life in patients undergoing lobectomy, with sustained benefits observed at the 6-month follow-up. Additionally, these exercises demonstrated superior lung function outcomes compared to traditional rehabilitation methods.
METHODS: Between January 2019 and December 2022, a retrospective review was conducted on patients with non-small cell lung cancer (NSCLC) who underwent lobectomy and lymph node dissection via video-assisted thoracoscopic surgery (VATS) at Daping hospital. Based on their postoperative rehabilitation methods, the patients were categorized into 2 groups: the traditional rehabilitation group and the pulmonary rehabilitation group. All patients underwent assessment using the Leicester cough questionnaire (LCQ) on the third postoperative day. Additionally, at the 6-month follow-up, patients\' LCQ scores and lung function were re-evaluated to assess the long-term effects of the pulmonary rehabilitation training programs.
RESULTS: Among the 276 patients meeting the inclusion criteria, 195 (70.7%) were in the traditional rehabilitation group, while 81 (29.3%) participated in the pulmonary rehabilitation group. The pulmonary rehabilitation group showed a significantly lower incidence of cough on the third postoperative day (16.0% vs 29.7%, P = .018) and higher LCQ scores in the somatic dimension (5.09 ± .81 vs 4.15 ± 1.22, P = .007) as well as in the total score (16.44 ± 2.86 vs 15.11 ± 2.51, P = .018, whereas there were no significant differences in psychiatric and sociological dimensions. At the 6-month follow-up, the pulmonary rehabilitation group continued to have a lower cough incidence (3.7% vs 12.8%, P = .022) and higher LCQ scores across all dimensions: somatic (6.19 ± .11 vs 5.75 ± 1.20, P = .035), mental (6.37 ± 1.19 vs 5.85 ± 1.22, P = .002), sociological (6.76 ± 1.22 vs 5.62 ± 1.08, P < .001), and total (18.22 ± 2.37 vs 16.21 ± 2.53, P < .001). Additionally, lung function parameters including FVC, FVC%, FEV1, FEV1%, MVV, MVV%, DLCO SB, and DLCO% were all significantly higher in the pulmonary rehabilitation group compared to the traditional group.
CONCLUSIONS: Pulmonary rehabilitation exercises significantly reduced the incidence of postoperative cough and improved cough-related quality of life in patients undergoing lobectomy, with sustained benefits observed at the 6-month follow-up. Additionally, these exercises demonstrated superior lung function outcomes compared to traditional rehabilitation methods.
Pulmonary rehabilitation exercises significantly reduced the incidence of postoperative cough and improved cough-related quality of life in patients undergoing lobectomy, with sustained benefits observed at the 6-month follow-up. Additionally, these exercises demonstrated superior lung function outcomes compared to traditional rehabilitation methods.
摘要：
背景：咳嗽是肺癌手术后的主要并发症，可能影响肺功能和生活质量。然而,治疗长期持续性术后咳嗽的有效治疗方法仍然难以捉摸.在这项研究中,我们调查了肺康复训练计划有效解决这一问题的潜力.
方法：在2019年1月至2022年12月之间，对大坪医院通过电视胸腔镜手术（VATS）进行肺叶切除和淋巴结清扫的非小细胞肺癌（NSCLC）患者进行了回顾性研究。根据他们的术后康复方法，将患者分为2组:传统康复组和肺康复组。所有患者在术后第三天使用莱斯特咳嗽问卷（LCQ）进行评估。此外,在6个月的随访中，我们重新评估患者的LCQ评分和肺功能,以评估肺康复训练计划的长期效果.
结果：在符合纳入标准的276例患者中，传统康复组195人(70.7%),而81人(29.3%)参加了肺康复组。肺康复组术后第3天咳嗽发生率明显较低(16.0%vs29.7%,P=.018），并且在躯体维度（5.09±.81vs4.15±1.22，P=.007）以及总分（16.44±2.86vs15.11±2.51，P=.018，而在精神病学和社会学维度上没有显着差异。在6个月的随访中，肺康复组咳嗽发生率继续较低(3.7%vs12.8%，P=.022）以及所有维度的LCQ得分更高：躯体（6.19±.11vs5.75±1.20，P=.035），精神（6.37±1.19vs5.85±1.22，P=.002），社会学（6.76±1.22vs5.62±1.08，P<.001），和总数（18.22±2.37vs16.21±2.53，P<.001）。此外,肺功能参数包括FVC，FVC%,FEV1,FEV1%,MVV,MVV%,DLCOSB,与传统组相比，肺康复组的DLCO％均显着升高。
结论：肺康复锻炼可显著降低肺叶切除术患者术后咳嗽的发生率，改善咳嗽相关生活质量，在6个月的随访中观察到持续的益处。此外,与传统的康复方法相比,这些锻炼显示了更好的肺功能结局.
肺康复锻炼可显著降低肺叶切除术患者术后咳嗽的发生率，改善咳嗽相关生活质量，在6个月的随访中观察到持续的益处。此外,与传统的康复方法相比,这些锻炼显示了更好的肺功能结局.
方法：在2019年1月至2022年12月之间，对大坪医院通过电视胸腔镜手术（VATS）进行肺叶切除和淋巴结清扫的非小细胞肺癌（NSCLC）患者进行了回顾性研究。根据他们的术后康复方法，将患者分为2组:传统康复组和肺康复组。所有患者在术后第三天使用莱斯特咳嗽问卷（LCQ）进行评估。此外,在6个月的随访中，我们重新评估患者的LCQ评分和肺功能,以评估肺康复训练计划的长期效果.
结果：在符合纳入标准的276例患者中，传统康复组195人(70.7%),而81人(29.3%)参加了肺康复组。肺康复组术后第3天咳嗽发生率明显较低(16.0%vs29.7%,P=.018），并且在躯体维度（5.09±.81vs4.15±1.22，P=.007）以及总分（16.44±2.86vs15.11±2.51，P=.018，而在精神病学和社会学维度上没有显着差异。在6个月的随访中，肺康复组咳嗽发生率继续较低(3.7%vs12.8%，P=.022）以及所有维度的LCQ得分更高：躯体（6.19±.11vs5.75±1.20，P=.035），精神（6.37±1.19vs5.85±1.22，P=.002），社会学（6.76±1.22vs5.62±1.08，P<.001），和总数（18.22±2.37vs16.21±2.53，P<.001）。此外,肺功能参数包括FVC，FVC%,FEV1,FEV1%,MVV,MVV%,DLCOSB,与传统组相比，肺康复组的DLCO％均显着升高。
结论：肺康复锻炼可显著降低肺叶切除术患者术后咳嗽的发生率，改善咳嗽相关生活质量，在6个月的随访中观察到持续的益处。此外,与传统的康复方法相比,这些锻炼显示了更好的肺功能结局.
肺康复锻炼可显著降低肺叶切除术患者术后咳嗽的发生率，改善咳嗽相关生活质量，在6个月的随访中观察到持续的益处。此外,与传统的康复方法相比,这些锻炼显示了更好的肺功能结局.
