Abstract：
OBJECTIVE: The vertebral artery (VA) is a vital branch of the subclavian artery, coursing through the transverse foramina of the cervical vertebrae, and playing a crucial role in irrigating the posterior region of the arterial cerebral circle, also known as the Polygon of Willis. Among the various possible alterations that can affect the VA, vertebral artery hypoplasia (HAV) emerges as a significant variant. This study aims to discern the anatomical features of HAV and its correlation with the clinical conditions of the posterior cerebral circulation.
METHODS: The databases Medline, Scopus, Web of Science, Google Scholar, CINAHL, and LILACS were searched until January 2024. Two authors independently performed the search, study selection, and data extraction. Methodological quality was evaluated with an assurance tool for anatomical studies (AQUA). Pooled prevalence was estimated using a random effects model.
RESULTS: A total of 24 studies met the established selection criteria, with a total of 8847 subjects. In this study, 6 articles were included for the meta-analysis with a total of subjects. The average prevalence of VAH reported in each study was 11% (95% CI 10-12%); the studies had a heterogeneity of 41% based on the funnel plot and a low risk of bias.
CONCLUSIONS: The prevalence of VAH is low, but in the presence of this condition, the changes are mainly in diameter rather than morphological. If it is present, some clinical safeguards must be taken to avoid complications such as stroke.
METHODS: The databases Medline, Scopus, Web of Science, Google Scholar, CINAHL, and LILACS were searched until January 2024. Two authors independently performed the search, study selection, and data extraction. Methodological quality was evaluated with an assurance tool for anatomical studies (AQUA). Pooled prevalence was estimated using a random effects model.
RESULTS: A total of 24 studies met the established selection criteria, with a total of 8847 subjects. In this study, 6 articles were included for the meta-analysis with a total of subjects. The average prevalence of VAH reported in each study was 11% (95% CI 10-12%); the studies had a heterogeneity of 41% based on the funnel plot and a low risk of bias.
CONCLUSIONS: The prevalence of VAH is low, but in the presence of this condition, the changes are mainly in diameter rather than morphological. If it is present, some clinical safeguards must be taken to avoid complications such as stroke.
摘要：
目的：椎动脉（VA）是锁骨下动脉的重要分支，穿过颈椎的横向孔，在动脉脑环后部的灌溉中起着至关重要的作用，也被称为威利斯的多边形。在可能影响VA的各种可能的改变中，椎动脉发育不全（HAV）是一个重要的变异。这项研究旨在辨别HAV的解剖特征及其与大脑后循环临床状况的相关性。
方法：数据库Medline，Scopus,WebofScience,谷歌学者，CINAHL,和LILACS被搜索到2024年1月。两位作者独立进行了搜索，研究选择，和数据提取。使用解剖学研究的保证工具（AQUA）评估了方法学质量。使用随机效应模型估计合并患病率。
结果：共有24项研究符合既定的选择标准，共8847个科目。在这项研究中,纳入6篇文章进行荟萃分析，共纳入受试者。每个研究中报告的VAH的平均患病率为11％（95％CI10-12％）；根据漏斗图，这些研究的异质性为41％，偏倚风险较低。
结论：VAH的患病率较低，但是在这种情况下，变化主要是直径而不是形态。如果它存在，必须采取一些临床预防措施来避免中风等并发症。
方法：数据库Medline，Scopus,WebofScience,谷歌学者，CINAHL,和LILACS被搜索到2024年1月。两位作者独立进行了搜索，研究选择，和数据提取。使用解剖学研究的保证工具（AQUA）评估了方法学质量。使用随机效应模型估计合并患病率。
结果：共有24项研究符合既定的选择标准，共8847个科目。在这项研究中,纳入6篇文章进行荟萃分析，共纳入受试者。每个研究中报告的VAH的平均患病率为11％（95％CI10-12％）；根据漏斗图，这些研究的异质性为41％，偏倚风险较低。
结论：VAH的患病率较低，但是在这种情况下，变化主要是直径而不是形态。如果它存在，必须采取一些临床预防措施来避免中风等并发症。
