Abstract：
Neosporosis is a worldwide parasitic disease caused by the protozoan Neospora caninum. It can cause economic losses to farmers due to its relationship with abortions and neonatal mortality in cows. Dogs play a key role in its spread as they are considered definitive hosts. In this study, we determined for the first time the seropositivity of N. caninum infection in dogs from Ecuador and evaluated potential risk factors. A total number of 339 free-roaming dogs from the three main regions of Ecuador (Coastal, Andean, and Amazonian regions) were included in the study and classified either as urban or rural dogs. Serum samples were collected from November 2018 to May 2019, and analyzed with a commercial ELISA test. An overall seropositivity of 6.8 % (CI: 95 %, 2.8 % - 11.7 %) was found in N. caninum infection with no statistical differences among regions or urban/rural dogs. This is the first surveillance of N. caninum in Ecuador, confirming a country-wide distribution of this pathogen. Considering the large populations of free-roaming dogs in Ecuador, a One Health approach for surveillance and managing N. caninum in dogs is needed to protect either livestock or wildlife.
摘要：
新孢子虫病是一种由原虫新孢子虫引起的世界性寄生虫病。由于与母牛流产和新生儿死亡率的关系，它可能会给农民造成经济损失。狗在其传播中起着关键作用，因为它们被认为是确定的宿主。在这项研究中,我们首次确定了厄瓜多尔犬的犬犬犬N.caninum感染的血清阳性，并评估了潜在的危险因素。来自厄瓜多尔三个主要地区的339只自由漫游的狗（沿海，安第斯,和亚马逊地区）被纳入研究，并归类为城市或农村犬。从2018年11月至2019年5月收集血清样品，并用商业ELISA测试进行分析。总体血清阳性为6.8%（CI：95%，2.8％-11.7％）在犬奈瑟菌感染中发现，地区或城市/农村犬之间没有统计学差异。这是厄瓜多尔首次对卡纳氏菌进行监测,证实了这种病原体在全国范围内的分布。考虑到厄瓜多尔有大量自由漫游的狗，a为了保护牲畜或野生动物，需要采取一种健康方法来监测和管理狗身上的犬只。
