Abstract：
Spinal cord infarction is a rare condition, accounting for only a small percentage of strokes. It can be classified into cervical and thoracolumbar infarctions, with various factors contributing to its occurrence. Sildenafil, a phosphodiesterase type 5 inhibitor commonly used for erectile dysfunction, has been associated with cardiovascular side effects, including transient hypotension. In this case report, we present the unusual occurrence of spinal cord infarction in a 65-year-old man who had self-administered high doses of sildenafil without a doctor\'s prescription. The patient experienced severe radicular pain in the lumbar region and subsequent weakness in the lower limbs. Evaluation revealed an anterior spinal cord infarction in the thoracic region, confirmed by MRI imaging. After excluding other potential causes, it was concluded that the intake of sildenafil likely led to systemic hypotension, resulting in spinal cord infarction. This case highlights the importance of considering sildenafil as a possible contributor to spinal cord infarction, particularly when used at high doses. Further studies are needed to better understand the relationship between sildenafil and vascular complications, including spinal cord infarction.
摘要：
脊髓梗塞是一种罕见的疾病，只占中风的一小部分。它可以分为颈和胸腰椎梗塞，各种因素促成了它的发生。西地那非,一种通常用于勃起功能障碍的5型磷酸二酯酶抑制剂，与心血管副作用有关，包括短暂性低血压.在这个案例报告中,我们介绍了1例65岁男性在没有医生处方的情况下自行服用高剂量西地那非的脊髓梗死异常发生.患者腰部出现严重的神经根性疼痛，随后下肢无力。评估显示胸部有脊髓前梗死，通过MRI成像证实。排除其他潜在原因后，结论是摄入西地那非可能导致全身性低血压，导致脊髓梗塞。这个案例强调了考虑西地那非可能导致脊髓梗塞的重要性，特别是在高剂量使用时。需要进一步的研究来更好地了解西地那非与血管并发症之间的关系，包括脊髓梗塞.
