Abstract:
Early disease detection is crucial since it raises the likelihood of treatment and considerably lowers the cost of therapy. Therefore, the improvement of human life and health depends on the development of quick, efficient, and credible biosensing methods. For improving the quality of biosensors, distinct nanostructures have been investigated; among these, carbon dots have gained much interest because of their great performance. Carbon dots, the essential component of fluorescence nanoparticles, having outstanding chemical characteristics, superb biocompatibility, chemical inertness, low toxicity and potential optical characteristics have attracted the researchers from every corner of the globe. Several carbon dots applications have been thoroughly investigated in recent decade, from optoelectronics to biomedical investigations. This review study primarily emphasizes the recent advancements in the field of biomass-derived carbon dots-based drug delivery, gene delivery and bioimaging, and highlights achievements in two major areas: in vivo applications that involve carbon dots absorption in zebrafish and mice, tumour therapeutics, and imaging-guided drug delivery. Additionally, the possible advantages, difficulties, and future possibilities of using carbon dots for biological applications are also explored.
摘要:
早期疾病检测至关重要,因为它提高了治疗的可能性并大大降低了治疗成本。因此,人类生活和健康的改善有赖于快速发展,高效,和可靠的生物传感方法。为了提高生物传感器的质量,已经研究了不同的纳米结构;其中,碳点因其出色的性能而获得了极大的兴趣。碳点,荧光纳米粒子的重要组成部分,具有突出的化学特性,极好的生物相容性,化学惰性,低毒性和潜在的光学特性吸引了来自全球各个角落的研究人员。近十年来,已经对几种碳点应用进行了彻底的研究,从光电子学到生物医学研究。这篇综述研究主要强调了生物质衍生碳点药物递送领域的最新进展,基因传递和生物成像,并强调了两个主要领域的成就:涉及斑马鱼和小鼠体内碳点吸收的体内应用,肿瘤治疗,和成像引导的药物输送。此外,可能的优势,困难,还探索了将碳点用于生物应用的未来可能性。