关键词: Conservative breast surgery Esthetic outcome Platelet rich plasma lipofilling

Mesh : Humans Female Platelet-Rich Plasma Breast Neoplasms / surgery Middle Aged Adipose Tissue / transplantation Adult Mammaplasty / methods Patient Satisfaction Postoperative Complications Mastectomy, Segmental

来  源:   DOI:10.3233/BD-230057   PDF(Pubmed)

Abstract:
UNASSIGNED: Fat transfer has been widely used after breast conservative surgery (BCS) where it aims to recover shapes as a simple, inexpensive, biocompatible method but the technique is not without complications. Platelet Rich Plasma (PRP) is a promising approach to enhance fat graft survival and subsequently improve the outcome. The aim of this study was to evaluate the effect of enriching fat graft with PRP for delayed correction of deformities after conservative surgery for breast cancer regarding esthetic outcome and incidence of complications.
UNASSIGNED: The current study included 50 female patients who were scheduled for delayed lipofilling for correction of deformities after conservative surgery for breast cancer. The studied patients were randomly allocated into 2 groups: Group I (G I) included 25 patients scheduled for PRP enriched lipoinjection and Group II (G II) included 25 patients scheduled for lipoinjection without PRP as a control group.
UNASSIGNED: Number of sessions of lipoinjection was significantly less in G I in comparison to G II (P = 0.024). During the 2nd session; the amounts of fat injected and harvested were significantly less in G I in comparison to G II (P = 0.049 and 0.001 respectively). Recipient site complications were significantly more evident in G II in comparison to G I (P = 0.01). Surgeon and patient satisfactions were significantly more evident in GI in comparison to G II (P = 0.005 and 0.029 respectively).
UNASSIGNED: The addition of PRP to fat grafts is a simple, cost-effective and safe method to improve esthetic outcome and decrease complications.
摘要:
脂肪转移在乳房保守手术(BCS)后已被广泛使用,旨在恢复形状,便宜,生物相容性方法,但该技术并非没有并发症。富血小板血浆(PRP)是提高脂肪移植物存活率并随后改善结果的有前途的方法。这项研究的目的是评估富含PRP的脂肪移植物对乳腺癌保守手术后畸形的延迟矫正效果以及并发症的发生率。
目前的研究包括50名女性患者,这些患者计划在乳腺癌保守手术后进行延迟脂肪填充以矫正畸形。将研究的患者随机分为2组:I组(GI)包括25例计划进行PRP富集点注射的患者,而II组(GII)包括25例计划进行无PRP点注射的患者作为对照组。
与GII相比,GI的点注射次数明显减少(P=0.024)。在第二次会议期间;与GII相比,GI中注射和收获的脂肪量显着减少(分别为P=0.049和0.001)。与GI相比,GII患者的受体部位并发症明显更明显(P=0.01)。与GII相比,GI的外科医生和患者满意度明显更高(分别为P=0.005和0.029)。
将PRP添加到脂肪移植物中是简单的,具有成本效益和安全的方法,以改善美学结果和减少并发症。
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