PDF(Pubmed)
Abstract：
UNASSIGNED: To evaluate the visual performance in adolescents undergoing orthokeratology (OrthoK) treatment with two different optical zone diameters (OZDs).
UNASSIGNED: This randomized, double-masked, self-controlled prospective study was conducted at Tianjin Eye Hospital (Tianjin, China) in June 2022. Thirty-six eligible schoolchildren were enrolled and fitted with corneal refractive therapy lenses with two sizes of OZDs (5 mm [5OZ] and 6 mm [6OZ]). Each participant was randomized to wear the 5OZ in one eye and the 6OZ in the contralateral eye. Subjective visual quality was assessed using visual acuity, refraction, contrast sensitivity function, and visual symptoms, and the objective optical quality was assessed using ocular higher order aberrations (HOAs) and modulation transfer function (MTF).
UNASSIGNED: Thirty-five myopic children completed a 1-month follow-up visit. The 5OZ lens induced significantly smaller treatment zone diameters than the 6OZ lens (P < 0.001). Subjective visual quality did not differ significantly between the two groups. Compared to baseline, aberrations of Z40, coma-like, spherical-like, and total HOAs in both groups increased significantly (P < 0.05). For the 3-mm pupils, spherical aberration in the 5OZ group was significantly higher than that in the 6OZ group (P < 0.05). The MTF value of the 6OZ group was significantly higher than that of 5OZ group for 0.3 and 1.5 cycles per degree for the 3-mm pupils (P = 0.006 and P = 0.026, respectively). However, HOAs or MTF did not differ significantly between the two groups for the 5-mm pupils.
UNASSIGNED: The difference induced by varying OZD was significant only in the smaller pupil condition. The selection of OZD in OrthoK designs in real-world patient management should be done while considering individual pupil size.
UNASSIGNED: This study revealed that the objective visual quality of small OZD lenses was only slightly affected for the small pupil size.
UNASSIGNED: This randomized, double-masked, self-controlled prospective study was conducted at Tianjin Eye Hospital (Tianjin, China) in June 2022. Thirty-six eligible schoolchildren were enrolled and fitted with corneal refractive therapy lenses with two sizes of OZDs (5 mm [5OZ] and 6 mm [6OZ]). Each participant was randomized to wear the 5OZ in one eye and the 6OZ in the contralateral eye. Subjective visual quality was assessed using visual acuity, refraction, contrast sensitivity function, and visual symptoms, and the objective optical quality was assessed using ocular higher order aberrations (HOAs) and modulation transfer function (MTF).
UNASSIGNED: Thirty-five myopic children completed a 1-month follow-up visit. The 5OZ lens induced significantly smaller treatment zone diameters than the 6OZ lens (P < 0.001). Subjective visual quality did not differ significantly between the two groups. Compared to baseline, aberrations of Z40, coma-like, spherical-like, and total HOAs in both groups increased significantly (P < 0.05). For the 3-mm pupils, spherical aberration in the 5OZ group was significantly higher than that in the 6OZ group (P < 0.05). The MTF value of the 6OZ group was significantly higher than that of 5OZ group for 0.3 and 1.5 cycles per degree for the 3-mm pupils (P = 0.006 and P = 0.026, respectively). However, HOAs or MTF did not differ significantly between the two groups for the 5-mm pupils.
UNASSIGNED: The difference induced by varying OZD was significant only in the smaller pupil condition. The selection of OZD in OrthoK designs in real-world patient management should be done while considering individual pupil size.
UNASSIGNED: This study revealed that the objective visual quality of small OZD lenses was only slightly affected for the small pupil size.
摘要：
■评估使用两种不同的光学区直径（OZD）进行角膜塑形术（OrthoK）治疗的青少年的视觉性能。
■这是随机的，双面蒙面,自身对照前瞻性研究在天津市眼科医院进行(天津，中国）2022年6月。36名符合条件的学童被纳入，并配备了两种尺寸的OZD（5mm[5OZ]和6mm[6OZ]）的角膜屈光治疗镜片。每个参与者被随机分配在一只眼睛中佩戴5OZ，在对侧眼睛中佩戴6OZ。使用视敏度评估主观视觉质量，折射,对比敏感度函数,和视觉症状，使用眼高阶像差（HOA）和调制传递函数（MTF）评估客观光学质量。
■35名近视儿童完成了为期1个月的随访。5OZ透镜诱导的治疗区直径明显小于6OZ透镜(P<0.001)。两组的主观视觉质量没有显着差异。与基线相比，Z40像差，昏迷样，球形，两组总HOA均显著升高(P<0.05)。对于3毫米的瞳孔，5OZ组球差明显高于6OZ组(P<0.05)。对于3-mm瞳孔，6OZ组的MTF值显着高于5OZ组，每度0.3和1.5个周期（分别为P=0.006和P=0.026）。然而,对于5毫米瞳孔，两组之间的HOA或MTF没有显着差异。
■改变OZD引起的差异仅在较小的瞳孔条件下是显着的。在现实世界的患者管理中，OrthoK设计中OZD的选择应在考虑个体瞳孔大小的同时进行。
■这项研究表明，对于小瞳孔大小，小型OZD镜头的客观视觉质量仅受到轻微影响。
■这是随机的，双面蒙面,自身对照前瞻性研究在天津市眼科医院进行(天津，中国）2022年6月。36名符合条件的学童被纳入，并配备了两种尺寸的OZD（5mm[5OZ]和6mm[6OZ]）的角膜屈光治疗镜片。每个参与者被随机分配在一只眼睛中佩戴5OZ，在对侧眼睛中佩戴6OZ。使用视敏度评估主观视觉质量，折射,对比敏感度函数,和视觉症状，使用眼高阶像差（HOA）和调制传递函数（MTF）评估客观光学质量。
■35名近视儿童完成了为期1个月的随访。5OZ透镜诱导的治疗区直径明显小于6OZ透镜(P<0.001)。两组的主观视觉质量没有显着差异。与基线相比，Z40像差，昏迷样，球形，两组总HOA均显著升高(P<0.05)。对于3毫米的瞳孔，5OZ组球差明显高于6OZ组(P<0.05)。对于3-mm瞳孔，6OZ组的MTF值显着高于5OZ组，每度0.3和1.5个周期（分别为P=0.006和P=0.026）。然而,对于5毫米瞳孔，两组之间的HOA或MTF没有显着差异。
■改变OZD引起的差异仅在较小的瞳孔条件下是显着的。在现实世界的患者管理中，OrthoK设计中OZD的选择应在考虑个体瞳孔大小的同时进行。
■这项研究表明，对于小瞳孔大小，小型OZD镜头的客观视觉质量仅受到轻微影响。
