关键词: Capsule Cryptococcus Glucuronoxylomannan

Mesh : Polysaccharides / chemistry Cryptococcus Antigens, Fungal / immunology Cryptococcus neoformans Fungal Capsules / metabolism chemistry Humans

来  源:   DOI:10.1007/978-1-0716-3722-7_24

Abstract:
Glucuronoxylomannan (GXM) is the principal capsular component in the Cryptococcus genus. This complex polysaccharide participates in numerous events related to the physiology and pathogenesis of Cryptococcus, which highlights the importance of establishing methods for its isolation and analysis. Conventional methods for GXM isolation have been extensively discussed in the literature. In this chapter, we describe two fast methods for obtaining extracellular fractions enriched with cryptococcal GXM.
摘要:
葡糖醛酸木甘露聚糖(GXM)是隐球菌属的主要荚膜成分。这种复合多糖参与了许多与隐球菌的生理和发病机制有关的事件。这突出了建立分离和分析方法的重要性。文献中广泛讨论了GXM分离的常规方法。在这一章中,我们描述了两种快速获得富含隐球菌GXM的细胞外级分的方法。
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