Abstract：
BACKGROUND: The two Canadian blood suppliers, Canadian Blood Services and Héma-Québec, removed the time-based deferral for men who have sex with men and adopted criteria assessing sexual risk behaviors. We report the impact of these changes on the safety and adequacy of the Canadian blood supply.
METHODS: Since 2022, all donors are asked if (1) they have had a new partner and (2) more than one sexual partner in the last 3 months. Donors answering yes to either question are asked if they had anal sex in the last 3 months; if yes, they are deferred for 3 months. We followed HIV rates for the 18 months before and 14 (Héma-Québec) or 18 months (Canadian Blood Services) post-implementation and interviewed HIV-positive whole blood donors. We assessed the number and characteristics of whole blood donors answering yes to the two first questions with or without deferral.
RESULTS: There were four HIV-positive donations out of 1,492,355 donations pre-implementation and four out of 1,447,772 post-implementation (0.27/100,000 vs. 0.28/100,000, p = 1.00). Post-implementation, one HIV-positive donor was non-compliant with multiple criteria, no risk factors were identified in the others. 3.2% of donors answered yes to questions (1) and/or (2); 0.17% were deferred for a new partner and/or more than one partner and anal sex. Deferral rates were highest in first time, younger donors, and similar in males and females.
CONCLUSIONS: Implementation of sexual risk behavior donor screening resulted in unchanged HIV rates to date and a manageable deferral rate.
METHODS: Since 2022, all donors are asked if (1) they have had a new partner and (2) more than one sexual partner in the last 3 months. Donors answering yes to either question are asked if they had anal sex in the last 3 months; if yes, they are deferred for 3 months. We followed HIV rates for the 18 months before and 14 (Héma-Québec) or 18 months (Canadian Blood Services) post-implementation and interviewed HIV-positive whole blood donors. We assessed the number and characteristics of whole blood donors answering yes to the two first questions with or without deferral.
RESULTS: There were four HIV-positive donations out of 1,492,355 donations pre-implementation and four out of 1,447,772 post-implementation (0.27/100,000 vs. 0.28/100,000, p = 1.00). Post-implementation, one HIV-positive donor was non-compliant with multiple criteria, no risk factors were identified in the others. 3.2% of donors answered yes to questions (1) and/or (2); 0.17% were deferred for a new partner and/or more than one partner and anal sex. Deferral rates were highest in first time, younger donors, and similar in males and females.
CONCLUSIONS: Implementation of sexual risk behavior donor screening resulted in unchanged HIV rates to date and a manageable deferral rate.
摘要：
背景：加拿大的两家血液供应商，加拿大血液服务机构和赫马-魁北克，删除了对男男性行为者的基于时间的延期，并采用了评估性风险行为的标准。我们报告了这些变化对加拿大血液供应的安全性和充足性的影响。
方法：自2022年以来，所有捐献者都被询问是否（1）他们有一个新伴侣和（2）在过去3个月中有一个以上的性伴侣。对任何一个问题回答“是”的捐赠者被问及他们在过去3个月中是否有过肛交；如果是，他们被推迟了三个月。我们跟踪了实施前18个月和实施后14个月（Héma-Québec）或18个月（加拿大血液服务）的艾滋病毒感染率，并采访了艾滋病毒阳性的全血献血者。我们评估了全血献血者的数量和特征，这些献血者对前两个问题有或没有推迟回答。
结果：在实施前的1,492,355捐款中有4例HIV阳性捐款，在实施后的1,447,772捐款中有4例HIV阳性捐款（0.27/100,000vs.0.28/100,000，p=1.00）。实施后，一名HIV阳性捐赠者不符合多个标准，未发现其他危险因素.3.2％的捐助者对问题（1）和/或（2）回答是；0.17％的人因新伴侣和/或多个伴侣和肛交而被推迟。延期率首次最高，年轻的捐赠者,男性和女性相似。
结论：实施性风险行为供者筛查导致迄今为止的HIV感染率和可控的延迟率不变。
方法：自2022年以来，所有捐献者都被询问是否（1）他们有一个新伴侣和（2）在过去3个月中有一个以上的性伴侣。对任何一个问题回答“是”的捐赠者被问及他们在过去3个月中是否有过肛交；如果是，他们被推迟了三个月。我们跟踪了实施前18个月和实施后14个月（Héma-Québec）或18个月（加拿大血液服务）的艾滋病毒感染率，并采访了艾滋病毒阳性的全血献血者。我们评估了全血献血者的数量和特征，这些献血者对前两个问题有或没有推迟回答。
结果：在实施前的1,492,355捐款中有4例HIV阳性捐款，在实施后的1,447,772捐款中有4例HIV阳性捐款（0.27/100,000vs.0.28/100,000，p=1.00）。实施后，一名HIV阳性捐赠者不符合多个标准，未发现其他危险因素.3.2％的捐助者对问题（1）和/或（2）回答是；0.17％的人因新伴侣和/或多个伴侣和肛交而被推迟。延期率首次最高，年轻的捐赠者,男性和女性相似。
结论：实施性风险行为供者筛查导致迄今为止的HIV感染率和可控的延迟率不变。
