关键词: Ochrobactrum anthropi aerobic gram-negative bacillus bacteremia non-enteric pneumonia virulence.

Mesh : Humans Ochrobactrum anthropi / isolation & purification pathogenicity Male Bacteremia / microbiology drug therapy complications Gram-Negative Bacterial Infections / microbiology complications drug therapy diagnosis Aged Anti-Bacterial Agents / therapeutic use Cross Infection / microbiology Pneumonia / microbiology

来  源:   DOI:10.2174/0118715265258415231018094653

Abstract:

Background: Ochrobactrum anthropi spp. is a non-enteric, aerobic gram-negative bacillus that has been reported to cause sepsis and occasionally bacteremia in both immunocompetent and immunocompromised hosts. This bacterium is capable of surviving in various habitats, but due to its affinity for aqueous environments, O. anthropi is hypothesized to have an affinity for indwelling plastic devices and other foreign bodies.

Case Presentation: We report a case of a 66 y/o male with a history of polysubstance abuse disorder admitted for toxic metabolic encephalopathy and found to have bronchopneumonia and bacteremia secondary to O. anthropi infection resulting in sepsis and cardiopulmonary arrest.

Discussion: Ochrobactrum spp. is an unusual pathogen of low virulence and has been noted to cause bacteremia and occasionally sepsis in both immunocompetent and immunosuppressed patients. Isolation of this pathogen in the appropriate setting should be considered a true pathogen and treated as such to avoid sequela of this infection.

Conclusion: This case report and literature review suggest that Ochrobactrum anthropi appears more frequently as a pathogen in nosocomial infections than suggested in the literature.

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摘要:

背景:嗜铬杆菌。是一种非肠溶的,据报道,需氧革兰氏阴性杆菌在免疫活性和免疫功能低下的宿主中都会引起败血症和偶尔的菌血症。这种细菌能够在不同的栖息地生存,但是由于它对水性环境的亲和力,假设O.anthropi对留置塑料装置和其他异物具有亲和力。

病例介绍:我们报告了一例66岁男性,有多物质滥用史,因中毒性代谢性脑病入院,发现有支气管肺炎和继发于人感染导致败血症和心肺骤停的菌血症。

讨论:苍白杆菌属。是一种不寻常的低毒力病原体,并且已经注意到在免疫活性和免疫抑制患者中引起菌血症和偶尔的败血症。在适当的环境中隔离该病原体应被认为是真正的病原体,并进行处理以避免这种感染的后遗症。

结论:本病例报告和文献综述表明,与文献中所建议的相比,人类嗜血杆菌作为病原体在医院感染中的出现频率更高。

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