Abstract：
OBJECTIVE: The aim of this study was to investigate the effectiveness of pan-immune inflammation value (PIV), systemic immune-inflammatory index (SII), and systemic inflammation response index (SIRI) in predicting mortality in acute cholecystitis (AC).
BACKGROUND: Abdominal pain is one of the most frequent complaints encountered by physicians at emergency department (ED).
METHODS: This clinical study is a cross-sectional study among patients admitted to the emergency department of a tertiary hospital and diagnosed with AC. Total survival curves were estimated by the Kaplan‒Meier method. Differences according to risk groups were determined by the log-rank test.
RESULTS: A total of 789 patients (survival: 737, non-survival: 52) diagnosed with AC were enrolled in the study. NLR and SII had an excellent diagnostic power in predicting 30-day mortality in the receiver operating characteristic (ROC) analysis, while the diagnostic power of SIRI and PIV was acceptable. It was observed that the probability of survival period decreased in the presence of NLR (>11.07), SII (>2315.18), SIRI (>6.55), and PIV (>1581.13) above the cut-off levels. The HRs of NLR, SII, SIRI, and PIV were 10.52, 7.44, 6.34, and 5.6, respectively.
CONCLUSIONS: NLR, SII, SIRI, and PIV may be useful markers in predicting 30-day mortality in patients with AC (Tab. 3, Fig. 5, Ref. 25).
BACKGROUND: Abdominal pain is one of the most frequent complaints encountered by physicians at emergency department (ED).
METHODS: This clinical study is a cross-sectional study among patients admitted to the emergency department of a tertiary hospital and diagnosed with AC. Total survival curves were estimated by the Kaplan‒Meier method. Differences according to risk groups were determined by the log-rank test.
RESULTS: A total of 789 patients (survival: 737, non-survival: 52) diagnosed with AC were enrolled in the study. NLR and SII had an excellent diagnostic power in predicting 30-day mortality in the receiver operating characteristic (ROC) analysis, while the diagnostic power of SIRI and PIV was acceptable. It was observed that the probability of survival period decreased in the presence of NLR (>11.07), SII (>2315.18), SIRI (>6.55), and PIV (>1581.13) above the cut-off levels. The HRs of NLR, SII, SIRI, and PIV were 10.52, 7.44, 6.34, and 5.6, respectively.
CONCLUSIONS: NLR, SII, SIRI, and PIV may be useful markers in predicting 30-day mortality in patients with AC (Tab. 3, Fig. 5, Ref. 25).
摘要：
目的：本研究的目的是研究泛免疫性炎症值（PIV）的有效性，全身免疫炎症指数（SII），和全身炎症反应指数（SIRI）预测急性胆囊炎（AC）的死亡率。
背景：腹痛是急诊科（ED）医生最常见的主诉之一。
方法：本临床研究是在三级医院急诊科收治并诊断为AC的患者中进行的横断面研究。总存活曲线采用Kaplan-Meier法估算。根据风险组的差异通过对数秩检验确定。
结果：共有789名诊断为AC的患者（存活：737名，非存活：52名）纳入研究。NLR和SII在受试者工作特征（ROC）分析中预测30天死亡率方面具有出色的诊断能力，而SIRI和PIV的诊断能力是可以接受的.据观察，在存在NLR(>11.07)的情况下，生存期的概率降低，SII(>2315.18),SIRI（>6.55），和PIV(>1581.13)高于截止水平。NLR的HR，SII,SIRI,PIV分别为10.52、7.44、6.34和5.6。
结论：NLR，SII,SIRI,和PIV可能是预测AC患者30天死亡率的有用标志物（表。3，图。5，参考。25).
背景：腹痛是急诊科（ED）医生最常见的主诉之一。
方法：本临床研究是在三级医院急诊科收治并诊断为AC的患者中进行的横断面研究。总存活曲线采用Kaplan-Meier法估算。根据风险组的差异通过对数秩检验确定。
结果：共有789名诊断为AC的患者（存活：737名，非存活：52名）纳入研究。NLR和SII在受试者工作特征（ROC）分析中预测30天死亡率方面具有出色的诊断能力，而SIRI和PIV的诊断能力是可以接受的.据观察，在存在NLR(>11.07)的情况下，生存期的概率降低，SII(>2315.18),SIRI（>6.55），和PIV(>1581.13)高于截止水平。NLR的HR，SII,SIRI,PIV分别为10.52、7.44、6.34和5.6。
结论：NLR，SII,SIRI,和PIV可能是预测AC患者30天死亡率的有用标志物（表。3，图。5，参考。25).
