关键词: Healthcare facilities Hospitalization Immunocompromised Mpox disease Outbreak

来  源:   DOI:10.1016/j.heliyon.2024.e30564   PDF(Pubmed)

Abstract:
UNASSIGNED: This sub-analysis seeks to delineate and characterize factors influencing hospitalization in individuals diagnosed with Mpox disease amidst the initial outbreak in Spain in the onset of 2022.
UNASSIGNED: Employing a non-probabilistic convenience sampling approach, a retrospective multicenter investigation was carried out to examine Monkeypox virus infection within Spanish healthcare facilities.
UNASSIGNED: The median duration of the disease was 16 days, with 4.2 % of cases resulting in hospitalization. There was a single ICU admission leading to fatality. Sequelae were observed in 2.3 % of cases. Multivariate analysis revealed that hospitalization decisions were influenced by immunosuppression and severe symptoms, including gastrointestinal, neurological, ear-nose-throat, and respiratory manifestations. Significant analytical parameter differences were restricted to hemoglobin levels at diagnosis.
UNASSIGNED: This study elucidates factors influencing hospitalization decisions for Monkeypox patients in Spain, emphasizing the importance of immunosuppression and extracutaneous symptoms involving the gastrointestinal, ear-nose-throat, and respiratory pathways. In summary, hospitalization determinations arise from the interplay of these crucial dimensions.
摘要:
此子分析旨在描述和表征在2022年西班牙首次爆发期间被诊断患有水痘疾病的个体的住院影响因素。
采用非概率便利抽样方法,我们进行了一项回顾性多中心调查,以检查西班牙医疗机构内的猴痘病毒感染情况.
疾病的中位持续时间为16天,4.2%的病例导致住院。有一次ICU入院导致死亡。2.3%的病例出现后遗症。多因素分析显示,住院决定受免疫抑制和严重症状的影响。包括胃肠,神经学,耳鼻喉,和呼吸道表现。显著的分析参数差异仅限于诊断时的血红蛋白水平。
这项研究阐明了影响西班牙猴痘患者住院决定的因素,强调免疫抑制和涉及胃肠道的皮肤外症状的重要性,耳鼻喉,和呼吸途径。总之,住院的决定源于这些关键维度的相互作用。
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