PDF(Pubmed)
Abstract：
UNASSIGNED: Cardiac magnetic resonance imaging (CMR) is an excellent non-invasive imaging tool in the assessment of patients with dilated cardiomyopathy (DCM). Few studies have analysed the findings in primary (idiopathic) DCM.
UNASSIGNED: To study the CMR features in primary DCM.
UNASSIGNED: We conducted a descriptive observational study on 20 adult patients with suspected or confirmed primary DCM. Each patient underwent a dedicated 3-Tesla CMR scan, and the findings were evaluated.
UNASSIGNED: Seventeen patients had systolic dysfunction with a reduced ejection fraction and elevated end-diastolic volume, 19 patients had contractile dysfunction in the form of global left ventricular hypokinesia, 13 patients showed no abnormal delayed contrast enhancement with gadolinium administration, and 7 patients showed abnormal late gadolinium enhancement patterns.
UNASSIGNED: In patients with primary DCM, CMR is a powerful diagnostic tool that can definitively establish the diagnosis, assess the severity of the disease, predict the risk of future adverse cardiovascular outcomes, check for complications, and assist in future follow-ups.
UNASSIGNED: What the study adds. Cardiac magnetic resonance imaging (CMR) is an excellent non-invasive imaging tool in the assessment of patients with primary dilated cardiomyopathy (DCM). Findings include global ventricular enlargement, systolic dysfunction (ejection fraction <40%), and elevated end-diastolic (≥140 mL) and end-systolic volumes. Global abnormal wall contractility is often seen. In DCM there is either no abnormal gadolinium enhancement or curvilinear mid-myocardial or subepicardial late gadolinium enhancement, unrelated to a coronary artery distribution.Implications of the findings. In patients with primary DCM, CMR provides powerful diagnostic and prognostic information. Enhanced awareness and understanding of this relatively uncommon condition among clinicians and radiologists would be of benefit in patient management and treatment.
UNASSIGNED: To study the CMR features in primary DCM.
UNASSIGNED: We conducted a descriptive observational study on 20 adult patients with suspected or confirmed primary DCM. Each patient underwent a dedicated 3-Tesla CMR scan, and the findings were evaluated.
UNASSIGNED: Seventeen patients had systolic dysfunction with a reduced ejection fraction and elevated end-diastolic volume, 19 patients had contractile dysfunction in the form of global left ventricular hypokinesia, 13 patients showed no abnormal delayed contrast enhancement with gadolinium administration, and 7 patients showed abnormal late gadolinium enhancement patterns.
UNASSIGNED: In patients with primary DCM, CMR is a powerful diagnostic tool that can definitively establish the diagnosis, assess the severity of the disease, predict the risk of future adverse cardiovascular outcomes, check for complications, and assist in future follow-ups.
UNASSIGNED: What the study adds. Cardiac magnetic resonance imaging (CMR) is an excellent non-invasive imaging tool in the assessment of patients with primary dilated cardiomyopathy (DCM). Findings include global ventricular enlargement, systolic dysfunction (ejection fraction <40%), and elevated end-diastolic (≥140 mL) and end-systolic volumes. Global abnormal wall contractility is often seen. In DCM there is either no abnormal gadolinium enhancement or curvilinear mid-myocardial or subepicardial late gadolinium enhancement, unrelated to a coronary artery distribution.Implications of the findings. In patients with primary DCM, CMR provides powerful diagnostic and prognostic information. Enhanced awareness and understanding of this relatively uncommon condition among clinicians and radiologists would be of benefit in patient management and treatment.
摘要：
■心脏磁共振成像（CMR）是评估扩张型心肌病（DCM）患者的出色非侵入性成像工具。很少有研究分析原发性（特发性）DCM的发现。
■研究主要DCM中的CMR特征。
■我们对20例疑似或确诊原发性DCM的成年患者进行了一项描述性观察性研究。每位患者都接受了专门的3特斯拉CMR扫描，并对调查结果进行了评估。
■17例患者有收缩功能障碍，射血分数降低，舒张末期容积升高，19例患者出现整体左心室功能减退形式的收缩功能障碍，13例患者使用钆没有异常延迟的对比增强，7例患者表现出异常的晚期钆增强模式。
■在原发性DCM患者中，CMR是一个强大的诊断工具，可以明确地建立诊断，评估疾病的严重程度，预测未来不良心血管结局的风险，检查并发症,并协助今后的后续行动。
■这项研究补充了什么。心脏磁共振成像（CMR）是评估原发性扩张型心肌病（DCM）患者的一种出色的非侵入性成像工具。研究结果包括整体心室扩大，收缩功能障碍（射血分数<40％），舒张末期（≥140mL）和收缩末期容积升高。经常看到整体异常的壁收缩性。在DCM中，没有异常的钆增强或心肌中段或心外膜晚期钆的曲线增强。与冠状动脉分布无关。对调查结果的影响。在原发性DCM患者中，CMR提供强大的诊断和预后信息。增强临床医生和放射科医师对这种相对罕见的疾病的认识和理解将对患者管理和治疗有益。
■研究主要DCM中的CMR特征。
■我们对20例疑似或确诊原发性DCM的成年患者进行了一项描述性观察性研究。每位患者都接受了专门的3特斯拉CMR扫描，并对调查结果进行了评估。
■17例患者有收缩功能障碍，射血分数降低，舒张末期容积升高，19例患者出现整体左心室功能减退形式的收缩功能障碍，13例患者使用钆没有异常延迟的对比增强，7例患者表现出异常的晚期钆增强模式。
■在原发性DCM患者中，CMR是一个强大的诊断工具，可以明确地建立诊断，评估疾病的严重程度，预测未来不良心血管结局的风险，检查并发症,并协助今后的后续行动。
■这项研究补充了什么。心脏磁共振成像（CMR）是评估原发性扩张型心肌病（DCM）患者的一种出色的非侵入性成像工具。研究结果包括整体心室扩大，收缩功能障碍（射血分数<40％），舒张末期（≥140mL）和收缩末期容积升高。经常看到整体异常的壁收缩性。在DCM中，没有异常的钆增强或心肌中段或心外膜晚期钆的曲线增强。与冠状动脉分布无关。对调查结果的影响。在原发性DCM患者中，CMR提供强大的诊断和预后信息。增强临床医生和放射科医师对这种相对罕见的疾病的认识和理解将对患者管理和治疗有益。
