PDF(Pubmed)
Abstract：
Cardiovascular disease (CVD) continues to pose a global health challenge, demonstrating significant disparities in occurrence among various populations. A wide number of research studies have indicated a higher prevalence of cardiovascular disease in South Asian immigrants compared to the local American population. The demand to improve the cardiovascular benefits of immigrants is increasing, which calls for further research with larger and more diverse population samples. This study will investigate the major causes of this variation, which include genetically diverse characteristics and changes in nutritional status among the study population groups. To assess the increase in the prevalence of cardiovascular disease among South Asian populations compared to the US population, a narrative review of accessible data is carried out. The data in support of the present document are from the Centre for Disease Prevention and Control, Statistics for Heart Diseases and Stroke 2023, a trend analysis about incidences of cardiac diseases and global burden in 2017, all dating back to the last two decades. Relevant articles from PubMed and Google Scholar have also been included, as appropriate, and their references are provided wherever necessary. Graphs for the geographical variations in disease incidence are produced using Microsoft Excel (Microsoft® Corp., Redmond, WA). The review shows that there is a significant decline in the prevalence of CVD among American citizens when compared to the steady increase in the number of cases among South Asians, which is attributed to the unique genetic predisposition of South Asians to be more prone to CVDs. The changing dietary habits also play an important role in the fall in HDL levels in South Asians when compared to Americans. This is driven by genetic disparities, including the APOA1 and APOA2 genes, and nutritional disparities, including variance in quality and quantity of dietary consumption. Addressing the escalating cases of CVD among South Asians necessitates additional research to enhance proactive preventive measures and implement screening programs specifically tailored to address prevalent risk factors within the population.
摘要：
心血管疾病（CVD）继续构成全球健康挑战，证明了不同人群之间发生的显著差异。大量研究表明，与美国当地人口相比，南亚移民的心血管疾病患病率更高。提高移民心血管效益的需求越来越大,这需要对更大、更多样化的人口样本进行进一步研究。这项研究将调查这种变化的主要原因，其中包括研究人群群体的遗传多样性特征和营养状况的变化。为了评估与美国人群相比，南亚人群中心血管疾病患病率的增加，对可访问数据进行叙述性审查。支持本文件的数据来自疾病预防和控制中心,2023年心脏病和中风统计数据，关于2017年心脏病发病率和全球负担的趋势分析，都可以追溯到过去二十年。PubMed和GoogleScholar的相关文章也被收录，在适当的情况下,并在必要时提供其参考。使用MicrosoftExcel制作疾病发病率地理变化的图表(Microsoft®Corp.,雷德蒙德,西澳）。审查表明，与南亚人病例数的稳定增长相比，美国公民的心血管疾病患病率显着下降，这归因于南亚人的独特遗传倾向更容易患CVD。与美国人相比，不断变化的饮食习惯在南亚人HDL水平下降中也起着重要作用。这是由遗传差异驱动的，包括APOA1和APOA2基因,和营养差异，包括饮食消费质量和数量的差异。为了应对南亚人心血管疾病的不断升级，需要进行更多的研究，以加强积极的预防措施，并实施专门针对人群中普遍存在的风险因素的筛查计划。
