PDF(Pubmed)
Abstract：
Herbal and dietary supplements (HDS) are a common etiology of drug induced liver injury and, specifically, Herbalife® supplements have been implicated. Hepatitis associated aplastic anemia (HAAA) is a rare and potentially fatal complication after acute hepatitis characterized by pancytopenia. While there have been rare cases of HDS leading to HAAA, no cases of Herbalife® induced liver injury leading to HAAA have been reported from this specific HDS. We report a unique case of severe aplastic anemia developing after sub-fulminant liver failure associated with chronic HDS use. This case illustrates the importance of warning the public about HDS as their use continues to increase. It is not only important to recognize HDS as etiology, but also for healthcare providers to carefully monitor these patients after resolution of liver injury for the development of HAAA.
摘要：
草药和膳食补充剂(HDS)是药物性肝损伤的常见病因,具体来说,涉及康宝莱®补充剂。肝炎相关再生障碍性贫血（HAAA）是以全血细胞减少为特征的急性肝炎后罕见且可能致命的并发症。虽然有罕见的HDS导致HAAA的病例，没有康宝莱®诱导的肝损伤导致HAAA的病例已经从这个特定的HDS报道。我们报告了与慢性HDS使用相关的亚暴发性肝衰竭后发展为严重再生障碍性贫血的独特病例。此案例说明了随着HDS的使用不断增加，警告公众有关HDS的重要性。它不仅重要的是认识到HDS的病因，但也为医疗保健提供者仔细监测这些患者后肝损伤的解决为发展的HAAA。
