Abstract：
A peptic ulcer is a lesion (sore) on the stomach lining, or duodenum. Peptic ulcers are probably a twentieth-century condition. The ulcer disease continues to be a significant source of worldwide morbidity and mortality. The Gastrointestinal ulcers and duodenal ulcers are considered the two most extreme types of peptic ulcers. Peptic ulcers are found to be caused by an excess of violent factors including Hydrochloric acid (HCL) pepsin, refluxed bile leukotrienes (LT), reactive oxygen species (ROS) and protective factors, these include mucus-bicarbonate barrier functions, prostaglandins (PGs), mucosal blood flow, cell regeneration and migration, non-enzymatic and enzymatic and certain growth factors. The primary cause of peptic ulcer disease is pylori infection and the use of NSAIDs. This review article underscores the importance of a multidisciplinary approach in the management of ulcers to improve patient outcomes and quality of life.
摘要：
消化性溃疡是胃粘膜上的病变（疮），或十二指肠。消化性溃疡可能是二十世纪的疾病。溃疡疾病仍然是全球发病率和死亡率的重要来源。胃肠道溃疡和十二指肠溃疡被认为是两种最极端的消化性溃疡。发现消化性溃疡是由过量的暴力因素引起的，包括盐酸（HCL）胃蛋白酶，回流胆汁白三烯（LT），活性氧（ROS）和保护因子，这些包括粘液-碳酸氢盐屏障功能，前列腺素（PGs），粘膜血流量，细胞再生和迁移，非酶和酶和某些生长因子。消化性溃疡的主要原因是幽门螺杆菌感染和使用NSAIDs。这篇综述文章强调了多学科方法在溃疡管理中的重要性，以改善患者的预后和生活质量。
