Abstract：
UNASSIGNED: This study constructed a comprehensive database of dietary antioxidants and total antioxidant capacity (TAC) to facilitate the estimation of daily antioxidant intake using a food frequency questionnaire (FFQ). This database was applied to 3 general population-based cohorts (n=195,961) within the Korean Genome and Epidemiology Study (KoGES).
UNASSIGNED: To establish a database of 412 foods derived from recipes of a 106-item FFQ, we followed a pre-established standardized protocol. This included the selection of source databases, matching of foods, substitution of unmatched items with identical foods and input of values, and assessment of coverage. For each food, the TAC was estimated by summing the individual antioxidant capacities, calculated by multiplying the amount of each antioxidant by its vitamin C equivalent antioxidant capacity.
UNASSIGNED: We identified 48 antioxidants across 5 classes: retinol, carotenoids, vitamins C and E, and flavonoids, with flavonoids divided into 7 subclasses. TAC values were then established. Coverage exceeded 90.0% for retinol, carotenoids, vitamin C, and vitamin E, while coverage for flavonoids was 60.9%. The daily intakes of 4 antioxidant classes-all but vitamin E-were higher in women than in men. The Ansan-Ansung cohort exhibited the highest levels of dietary TAC, vitamin E, and flavonoids, while the Health Examinees Study cohort displayed the highest values for retinol, carotenoids, and vitamin C.
UNASSIGNED: We customized a comprehensive antioxidant database for the KoGES FFQ, achieving relatively high coverage. This expansion could support research investigating the impact of dietary antioxidants on the development of chronic diseases targeted by the KoGES.
UNASSIGNED: To establish a database of 412 foods derived from recipes of a 106-item FFQ, we followed a pre-established standardized protocol. This included the selection of source databases, matching of foods, substitution of unmatched items with identical foods and input of values, and assessment of coverage. For each food, the TAC was estimated by summing the individual antioxidant capacities, calculated by multiplying the amount of each antioxidant by its vitamin C equivalent antioxidant capacity.
UNASSIGNED: We identified 48 antioxidants across 5 classes: retinol, carotenoids, vitamins C and E, and flavonoids, with flavonoids divided into 7 subclasses. TAC values were then established. Coverage exceeded 90.0% for retinol, carotenoids, vitamin C, and vitamin E, while coverage for flavonoids was 60.9%. The daily intakes of 4 antioxidant classes-all but vitamin E-were higher in women than in men. The Ansan-Ansung cohort exhibited the highest levels of dietary TAC, vitamin E, and flavonoids, while the Health Examinees Study cohort displayed the highest values for retinol, carotenoids, and vitamin C.
UNASSIGNED: We customized a comprehensive antioxidant database for the KoGES FFQ, achieving relatively high coverage. This expansion could support research investigating the impact of dietary antioxidants on the development of chronic diseases targeted by the KoGES.
摘要：
■本研究构建了饮食抗氧化剂和总抗氧化能力（TAC）的综合数据库，以方便使用食物频率问卷（FFQ）估算每日抗氧化剂摄入量。该数据库应用于韩国基因组和流行病学研究（KoGES）中的3个基于一般人群的队列（n=195,961）。
■要建立从106项FFQ食谱中提取的412种食物的数据库，我们遵循预先建立的标准化方案.这包括选择源数据库，食物的搭配，用相同的食物和价值输入替换无与伦比的物品，和覆盖率评估。对于每一种食物，TAC是通过对个体抗氧化能力求和来估计的，通过将每种抗氧化剂的量乘以其维生素C等效抗氧化能力来计算。
■我们确定了5类的48种抗氧化剂：视黄醇，类胡萝卜素，维生素C和E,和类黄酮，黄酮类化合物分为7个亚类。然后建立TAC值。视黄醇的覆盖率超过90.0%，类胡萝卜素，维生素C,和维生素E,类黄酮覆盖率为60.9%。除维生素E外，4种抗氧化剂的每日摄入量均高于男性。Ansan-Ansung队列显示出最高水平的饮食TAC，维生素E,和类黄酮，虽然健康检查者研究队列显示视黄醇的最高值，类胡萝卜素，和维生素C。
■我们为KoGESFFQ定制了一个全面的抗氧化剂数据库，实现相对较高的覆盖率。这种扩展可以支持研究饮食抗氧化剂对KoGES靶向慢性疾病发展的影响。
■要建立从106项FFQ食谱中提取的412种食物的数据库，我们遵循预先建立的标准化方案.这包括选择源数据库，食物的搭配，用相同的食物和价值输入替换无与伦比的物品，和覆盖率评估。对于每一种食物，TAC是通过对个体抗氧化能力求和来估计的，通过将每种抗氧化剂的量乘以其维生素C等效抗氧化能力来计算。
■我们确定了5类的48种抗氧化剂：视黄醇，类胡萝卜素，维生素C和E,和类黄酮，黄酮类化合物分为7个亚类。然后建立TAC值。视黄醇的覆盖率超过90.0%，类胡萝卜素，维生素C,和维生素E,类黄酮覆盖率为60.9%。除维生素E外，4种抗氧化剂的每日摄入量均高于男性。Ansan-Ansung队列显示出最高水平的饮食TAC，维生素E,和类黄酮，虽然健康检查者研究队列显示视黄醇的最高值，类胡萝卜素，和维生素C。
■我们为KoGESFFQ定制了一个全面的抗氧化剂数据库，实现相对较高的覆盖率。这种扩展可以支持研究饮食抗氧化剂对KoGES靶向慢性疾病发展的影响。
