CD37 是医治急性髓系白血病的平安嵌合抗原受体靶点。
关键词: AML CAR T cell CD37 acute myeloid leukemia chimeric antigen receptor hematopoietic stem cell immunotherapy patient-derived xenograft
Mesh : Humans Leukemia, Myeloid, Acute / therapy immunology pathology Receptors, Chimeric Antigen / immunology metabolism Animals Immunotherapy, Adoptive / methods Mice Tetraspanins / immunology Cell Line, Tumor T-Lymphocytes / immunology Antigens, Differentiation, Myelomonocytic / metabolism immunology Female Male Antigens, Neoplasm
来 源:
DOI:10.1016/j.xcrm.2024.101572
PDF(Pubmed)