PDF(Pubmed)
Abstract：
Pigmented hairy epidermal nevus, also known as Becker\'s nevus, has a typical description as a unilateral, hairy in appearance, light to dark brown patch with an irregular but clearly defined border. However, the exact aetiopathogenesis is still poorly comprehended. We report the case of a 19-year-old female who presented with asymptomatic brownish-pigmented macular lesions on the right breast that had slowly increased in size over the past three years. Upon cutaneous inspection, the right breast had 3-5 mm rounded and oval perifollicular macules that ranged from light to dark brown hue without increased hair growth. The macules were discrete and in no particular pattern. Dermoscopy of the lesions showed well-defined perifollicular hypopigmentation surrounded by a pigmented network-like pattern. Histopathology of a punch biopsy taken from one of the follicular lesions demonstrated an increase in basal layer pigmentation with elongation of rete ridges and acanthosis, consistent with Becker\'s nevus. The patient underwent three sittings of diode laser therapy, once in four weeks, with slight improvement in pigmentation.
摘要：
色素沉着的毛状表皮痣，也被称为贝克尔的痣，有一个典型的单方面描述，毛茸茸的外观，浅棕色至深棕色斑块，具有不规则但清晰的边界。然而,确切的病因仍然知之甚少。我们报告了一名19岁女性的病例，该女性在右乳房上出现无症状的褐色色素黄斑病变，该病变在过去三年中逐渐增大。经皮肤检查,右乳房有3-5毫米的圆形和椭圆形的毛囊周围黄斑，范围从浅色到深棕色，没有增加的头发生长。斑斑是离散的，没有特定的模式。病变的皮肤镜检查显示出明确的毛囊周围色素沉着减退，周围呈色素网状。从其中一个滤泡性病变获取的穿刺活检的组织病理学表明，随着网状脊和棘皮的延长，基底层色素沉着增加。与贝克尔的痣一致。病人接受了三次二极管激光治疗，四周一次,色素沉着略有改善。
