PDF(Pubmed)
Abstract：
UNASSIGNED: Poland syndrome is an occasional congenital malformation characterized by unilateral chest wall dysplasia and ipsilateral upper limb abnormalities. An association between Poland syndrome and breast cancer has been reported, but no clear etiological link between Poland syndrome and breast tumors has been established. We report a case of Poland syndrome combined with breast cancer and analyzed the clinical features of breast cancer in this case and its influence on the choice of treatment for breast cancer.
UNASSIGNED: In February 2022, we admitted a 47-year-old woman with Poland syndrome involving the right limb combined with right-sided breast cancer. After admission, the patient was given eight cycles of neoadjuvant therapy and underwent a modified radical mastectomy on September 7, 2022. Absence of right pectoralis major muscle and pectoralis minor muscle, thoracic deformity, and an adhesive band along the side of the sternum to the right axilla were observed during the operation. After surgery, the incision achieved grade-A healing, and the targeted therapy was continued for 1 year. The patient was followed up for 8 months after surgery, and the limb function of the affected side recovered well, and no obvious subcutaneous effusion, flap necrosis, upper limb edema, and other complications were observed.
UNASSIGNED: The anatomic variation of patients with Poland syndrome has some influence on the selection of surgical methods for breast cancer, but whether it would affect the prognosis of patients is unknown. To clarify the relationship between Poland syndrome and breast cancer, we need more cases to conduct etiological studies in the future.
UNASSIGNED: In February 2022, we admitted a 47-year-old woman with Poland syndrome involving the right limb combined with right-sided breast cancer. After admission, the patient was given eight cycles of neoadjuvant therapy and underwent a modified radical mastectomy on September 7, 2022. Absence of right pectoralis major muscle and pectoralis minor muscle, thoracic deformity, and an adhesive band along the side of the sternum to the right axilla were observed during the operation. After surgery, the incision achieved grade-A healing, and the targeted therapy was continued for 1 year. The patient was followed up for 8 months after surgery, and the limb function of the affected side recovered well, and no obvious subcutaneous effusion, flap necrosis, upper limb edema, and other complications were observed.
UNASSIGNED: The anatomic variation of patients with Poland syndrome has some influence on the selection of surgical methods for breast cancer, but whether it would affect the prognosis of patients is unknown. To clarify the relationship between Poland syndrome and breast cancer, we need more cases to conduct etiological studies in the future.
摘要：
■波兰综合征是一种偶然的先天性畸形，其特征是单侧胸壁发育不良和同侧上肢异常。波兰综合征和乳腺癌之间的关联已被报道，但波兰综合征和乳腺肿瘤之间没有明确的病因联系.我们报告了一例波兰综合征合并乳腺癌的病例，并分析了该病例中乳腺癌的临床特征及其对乳腺癌治疗选择的影响。
■2022年2月，我们收治了一名患有波兰综合征的47岁女性，涉及右肢合并右侧乳腺癌。入院后,患者接受了8个周期的新辅助治疗,并于2022年9月7日接受了改良根治术.右侧胸大肌和胸大肌缺失,胸廓畸形,术中观察到沿胸骨一侧至右腋下的粘合带。手术后,切口达到A级愈合,靶向治疗持续1年.术后随访8个月,患侧肢体功能恢复良好，无明显皮下积液,皮瓣坏死，上肢水肿,并观察其他并发症。
■波兰综合征患者的解剖变异对乳腺癌手术方法的选择有一定影响，但是否会影响患者的预后尚不清楚。阐明波兰综合征与乳腺癌的关系,我们将来需要更多病例进行病因研究。
■2022年2月，我们收治了一名患有波兰综合征的47岁女性，涉及右肢合并右侧乳腺癌。入院后,患者接受了8个周期的新辅助治疗,并于2022年9月7日接受了改良根治术.右侧胸大肌和胸大肌缺失,胸廓畸形,术中观察到沿胸骨一侧至右腋下的粘合带。手术后,切口达到A级愈合,靶向治疗持续1年.术后随访8个月,患侧肢体功能恢复良好，无明显皮下积液,皮瓣坏死，上肢水肿,并观察其他并发症。
■波兰综合征患者的解剖变异对乳腺癌手术方法的选择有一定影响，但是否会影响患者的预后尚不清楚。阐明波兰综合征与乳腺癌的关系,我们将来需要更多病例进行病因研究。
