PDF(Pubmed)
Abstract：
Several new ultrasound tools have been developed to further evaluate breast lesions detected on B-mode ultrasound. Strain elastography (SRE) was developed to assess the likelihood of malignancy of lesions based on their stiffness. This has been incorporated into the latest edition of the American College of Radiology (ACR) Breast Imaging Reporting and Data System (BI-RADS) lexicon and atlas. However, no agreed cut-off stiffness values have been established to distinguish benign from malignant lesions making the translation into routine clinical practice difficult. Superb microvascular imaging (SMI) was developed to better evaluate the vascularity within sonographic lesions and assess their likelihood of malignancy. However, there is also no agreed cut-off value for vascular index (VI) to distinguish between benign and malignant lesions. MicroPure was developed to better visualize and evaluate calcifications seen on ultrasound. Its effective use in breast screening and evaluating the calcifications detected for likelihood of malignancy have not been established. This article describes the original intended uses of these applications and reviews the studies evaluating them, showing the varying success of the translation of these tools into routine clinical practice. Also described are some other uses of these tools for which they were not originally intended. This illustrates the importance of being perceptive to alternative uses of imaging tools in their translation from bench to bedside.
摘要：
已经开发了几种新的超声工具来进一步评估在B型超声上检测到的乳腺病变。建立了应变弹性成像（SRE）以根据病变的硬度评估病变恶性的可能性。这已被纳入美国放射学院（ACR）乳腺成像报告和数据系统（BI-RADS）词典和地图集的最新版本。然而,目前尚未确定可区分良性和恶性病变的界限刚度值,这使得将其转化为常规临床实践变得困难.开发了出色的微血管成像（SMI），以更好地评估超声检查病变内的血管分布并评估其恶性肿瘤的可能性。然而,血管指数(VI)也没有一致的临界值来区分良性和恶性病变.开发了MicroPure以更好地可视化和评估在超声上看到的钙化。尚未确定其在乳腺筛查和评估检测到的钙化是否有恶性肿瘤的有效用途。本文介绍了这些应用程序的原始预期用途，并回顾了评估它们的研究，显示了将这些工具转化为常规临床实践的不同成功。还描述了这些工具的一些其他用途，它们最初不是针对这些用途的。这说明了在从工作台到床边的转换中感知成像工具的替代用途的重要性。
