Abstract：
Programmed cell death 1 (PD-1), a key immune checkpoint receptor, has been extensively studied for its role in regulating immune responses in cancer. However, recent research has unveiled a complex and dual role for PD-1 in tumorigenesis. While PD-1 is traditionally associated with immune cells, this article explores its expression in various cancer cells and its impact on cancer progression. PD-1\'s functions extend beyond immune regulation, as it has been found to both promote and suppress tumor growth, depending on the cancer type. These findings have significant implications for the future of cancer treatment and our understanding of the immune response in the context of cancer. This article calls for further research into the multifaceted roles of PD-1 to optimize its therapeutic potential and improve patient outcomes in the fight against cancer.
摘要：
程序性细胞死亡1（PD-1），一个关键的免疫检查点受体，它在调节癌症免疫反应中的作用已被广泛研究。然而,最近的研究揭示了PD-1在肿瘤发生中的复杂和双重作用。虽然PD-1传统上与免疫细胞相关，本文探讨了其在各种癌细胞中的表达及其对癌症进展的影响。PD-1的功能超出了免疫调节，因为它被发现可以促进和抑制肿瘤的生长，取决于癌症类型。这些发现对癌症治疗的未来以及我们对癌症背景下免疫反应的理解具有重要意义。本文呼吁进一步研究PD-1的多方面作用，以优化其治疗潜力并改善患者在抗击癌症方面的预后。
