Abstract：
Repairing and regenerating damaged tissues or organs, and restoring their functioning has been the ultimate aim of medical innovations. \'Reviving healthcare\' blends tissue engineering with alternative techniques such as hydrogels, which have emerged as vital tools in modern medicine. Additive manufacturing (AM) is a practical manufacturing revolution that uses building strategies like molding as a viable solution for precise hydrogel manufacturing. Recent advances in this technology have led to the successful manufacturing of hydrogels with enhanced reproducibility, accuracy, precision, and ease of fabrication. Hydrogels continue to metamorphose as the vital compatible bio-ink matrix for AM. AM hydrogels have paved the way for complex 3D/4D hydrogels that can be loaded with drugs or cells. Bio-mimicking 3D cell cultures designed via hydrogel-based AM is a groundbreaking in-vivo assessment tool in biomedical trials. This brief review focuses on preparations and applications of additively manufactured hydrogels in the biomedical spectrum, such as targeted drug delivery, 3D-cell culture, numerous regenerative strategies, biosensing, bioprinting, and cancer therapies. Prevalent AM techniques like extrusion, inkjet, digital light processing, and stereo-lithography have been explored with their setup and methodology to yield functional hydrogels. The perspectives, limitations, and the possible prospects of AM hydrogels have been critically examined in this study.
摘要：
修复和再生受损的组织或器官，恢复它们的功能一直是医学创新的最终目标。“复兴医疗保健”将组织工程与水凝胶等替代技术融合在一起，已经成为现代医学的重要工具。增材制造（AM）是一种实用的制造革命，它使用诸如成型之类的构建策略作为精确水凝胶制造的可行解决方案。该技术的最新进展已导致成功制造具有增强的再现性的水凝胶，准确度,精度,和易于制造。水凝胶继续变质，成为AM的重要相容生物墨水基质。AM水凝胶为可以装载药物或细胞的复杂3D/4D水凝胶铺平了道路。通过基于水凝胶的AM设计的生物模拟3D细胞培养是生物医学试验中开创性的体内评估工具。这篇简短的综述集中在生物医学领域增材制造水凝胶的制备和应用，例如靶向药物递送，3D细胞培养,许多再生策略，生物传感，生物打印,和癌症治疗。流行的AM技术，如挤压，喷墨,数字光处理，和立体光刻技术已经通过它们的设置和方法进行了探索，以产生功能性水凝胶。的观点，局限性,在这项研究中，对AM水凝胶的可能前景进行了严格的研究。
