Abstract：
OBJECTIVE: To evaluate the importance of the status of posterior vitreous in eyes with endophthalmitis following intravitreal anti-vascular endothelial growth factor (anti-VEGF).
METHODS: The absence or existence of posterior vitreous detachment (PVD) was elicited in 23 eyes of 23 patients with injection related endophthalmitis, during pars plana vitrectomy (PPV) and compared with 24 control eyes of 24 patients who received intravitreal anti-VEGF without any complication.
RESULTS: Thirtten (54.2%) out of 24 patients in the control group had full PVD, whereas only 2 (9.5%) out of 23 eyes in endophthalmitis group (p < 0.001) had full PVD. In all eyes without PVD, posterior vitreous was inducted to be detached at least from optic nerve and macular area without any iatrogenic tear.
CONCLUSIONS: The absence of PVD is a factor that increases the risk of endophthalmitis after intravitreal injections. Uncomplicated separation of the posterior vitreous from the retina in PPV contributes to better prognosis.
METHODS: The absence or existence of posterior vitreous detachment (PVD) was elicited in 23 eyes of 23 patients with injection related endophthalmitis, during pars plana vitrectomy (PPV) and compared with 24 control eyes of 24 patients who received intravitreal anti-VEGF without any complication.
RESULTS: Thirtten (54.2%) out of 24 patients in the control group had full PVD, whereas only 2 (9.5%) out of 23 eyes in endophthalmitis group (p < 0.001) had full PVD. In all eyes without PVD, posterior vitreous was inducted to be detached at least from optic nerve and macular area without any iatrogenic tear.
CONCLUSIONS: The absence of PVD is a factor that increases the risk of endophthalmitis after intravitreal injections. Uncomplicated separation of the posterior vitreous from the retina in PPV contributes to better prognosis.
摘要：
目的：评估玻璃体腔注射抗血管内皮生长因子（anti-VEGF）后眼内炎患者玻璃体后状态的重要性。
方法：对23例注射相关性眼内炎患者的23只眼进行玻璃体后脱离(PVD)检查。在平坦部玻璃体切除术（PPV）期间，并与接受玻璃体腔注射抗VEGF无任何并发症的24例患者的24只对照眼进行比较。
结果：对照组24例患者中有13例（54.2%）患有完全PVD，而眼内炎组(p<0.001)23只眼中只有2只(9.5%)有完全PVD.在所有没有PVD的眼睛里，诱导后玻璃体至少从视神经和黄斑区脱离，没有任何医源性撕裂。
结论：不存在PVD是玻璃体内注射后增加眼内炎风险的因素。在PPV中，后玻璃体与视网膜的简单分离有助于更好的预后。
方法：对23例注射相关性眼内炎患者的23只眼进行玻璃体后脱离(PVD)检查。在平坦部玻璃体切除术（PPV）期间，并与接受玻璃体腔注射抗VEGF无任何并发症的24例患者的24只对照眼进行比较。
结果：对照组24例患者中有13例（54.2%）患有完全PVD，而眼内炎组(p<0.001)23只眼中只有2只(9.5%)有完全PVD.在所有没有PVD的眼睛里，诱导后玻璃体至少从视神经和黄斑区脱离，没有任何医源性撕裂。
结论：不存在PVD是玻璃体内注射后增加眼内炎风险的因素。在PPV中，后玻璃体与视网膜的简单分离有助于更好的预后。
