Abstract:
Dr. Henrik Sjögren after whom Sjögren\'s Syndrome is named, was a Swedish ophthalmologist who identified the syndrome which had three main symptoms namely, dry eyes, dry mouth, and arthritis. His contributions also highlighted the systemic complications of the syndrome which made our understanding of this disease better. Since then, there have been several studies on Sjögren\'s Syndrome (SS) of which two of them have changed the perception of the disease\'s prevalence. The first was a British study in the late 1990s which indicated this syndrome was no more a rare condition. The second is a 2008 study in the US which placed the syndrome as the second most prevalent autoimmune disease after rheumatoid arthritis (RA). Being one of the most prevalent autoimmune disease, there is a pressing need for a more profound and comprehensive understanding of the syndrome. This review endeavors to offer a comprehensive overview of the disease, encompassing its prevalence, manifestations, mechanisms, genetic factors, diagnostic methods, and treatment options. This review additionally offers the āyurvedic viewpoint on SS and its symptoms. This supplementary insight has the potential to contribute to the development of an integrated and holistic approach to managing the condition.
摘要:
HenrikSjögren博士以Sjögren综合征的名字命名,是一位瑞典眼科医生,他确定了这种综合征有三个主要症状,即,干眼,口干,和关节炎。他的贡献还强调了该综合征的系统性并发症,这使我们对这种疾病的理解更好。从那以后,已经有几项关于干燥综合征(SS)的研究,其中两项改变了人们对该疾病患病率的看法。首先是1990年代后期的一项英国研究,该研究表明这种综合症不再是罕见的疾病。第二个是2008年在美国进行的一项研究,该研究将该综合征列为仅次于类风湿性关节炎(RA)的第二大最普遍的自身免疫性疾病。作为最常见的自身免疫性疾病之一,迫切需要对这种综合症有更深刻和全面的认识。这篇综述试图提供对这种疾病的全面概述,包括其患病率,表现,机制,遗传因素,诊断方法,和治疗选择。这篇评论还提供了阿育吠陀对SS及其症状的观点。这种补充见解有可能有助于开发一种综合和整体的方法来管理病情。