m - [18F] FET 和 [18F] FET - OMe 作为用于脑肿瘤成像的新型 [18F] FET 类似物的放射合成和临床前评估。
关键词: [18F]FET brain tumor imaging fluorine-18 positron emission tomography radiopharmaceuticals
Mesh : Animals Brain Neoplasms / diagnostic imaging metabolism Humans Mice Tyrosine / analogs & derivatives chemistry Cell Line, Tumor Positron-Emission Tomography / methods Radiopharmaceuticals / pharmacokinetics chemistry chemical synthesis Tissue Distribution Fluorine Radioisotopes / chemistry Glioblastoma / diagnostic imaging metabolism Mice, Nude Large Neutral Amino Acid-Transporter 1 / metabolism Brain / diagnostic imaging metabolism
来 源:
DOI:10.1021/acs.molpharmaceut.3c01215
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