PDF(Pubmed)
Abstract：
Tick-borne flaviviruses and Borrelia spp. are globally spread pathogens of zoonotic potential that are maintained by a transmission cycle at the interface between ticks and vertebrate hosts, mainly wild animals. Aside data on pathogen burden in ticks, information on the status of various hosts relative to infection is important to acquire. We reviewed how those infections have been studied in wildlife host species in the field to discuss how collected data provided relevant epidemiological information and to identify needs for further studies. The literature was screened for observational studies on pathogen or antibody detection for tick-borne Borrelia spp. and flaviviruses in wildlife host animals. Overall, Borrelia spp. were more studied (73% of case studies, representing 297 host species) than flaviviruses (27% of case studies, representing 114 host species). Studies on both Borrelia spp. and flaviviruses focused mainly on the same species, namely bank vole and yellow-necked mouse. Most studies were order-specific and cross-sectional, reporting prevalence at various locations, but with little insight into the underlying epidemiological dynamics. Host species with potential to act as reservoir hosts of these pathogens were neglected, notably birds. We highlight the necessity of collecting both demographics and infection data in wildlife studies, and to consider communities of species, to better estimate zoonotic risk potential in the One Health context.
摘要：
蜱传黄病毒和疏螺旋体属。是全球传播的人畜共患潜力病原体，由蜱和脊椎动物宿主之间的界面上的传播周期维持，主要是野生动物。除了蜱中病原体负担的数据，获取各种宿主相对于感染的状态信息很重要。我们回顾了如何在该领域的野生生物宿主物种中研究这些感染，以讨论收集的数据如何提供相关的流行病学信息并确定进一步研究的需求。筛选了文献，以进行有关tick传播的疏螺旋体的病原体或抗体检测的观察性研究。和野生动物宿主动物中的黄病毒。总的来说,疏螺旋体属。进行了更多的研究(73%的案例研究，代表297种宿主物种)比黄病毒(27%的案例研究，代表114个宿主物种)。对两种疏螺旋体的研究。黄病毒主要集中在同一物种上，即银行田鼠和黄颈老鼠。大多数研究是针对特定顺序和横截面的，报告不同地点的患病率，但对潜在的流行病学动态知之甚少。有可能作为这些病原体的宿主宿主的宿主物种被忽略，尤其是鸟类。我们强调了在野生动物研究中收集人口统计和感染数据的必要性，并考虑物种群落，更好地估计一个健康背景下的人畜共患风险潜力。
