PDF(Pubmed)
Abstract：
UNASSIGNED: Cerebral microbleeds (MBs) are recently described entity on magnetic resonance (MR) neuroimaging and are considered one of the markers of small vessel disease. We aimed to study the clinicoradiological features of cerebral MBs that were diagnosed in MR neuroimaging.
UNASSIGNED: We studied 109 South Indian patients, who presented to a tertiary care institution for MR neuroimaging with cerebral MBs as diagnosed on MR neuroimaging based on either the gradient T2* imaging or susceptibility-weighted imaging. The clinical details and coexisting MR features of infarcts, macrohemorrhages, lacunar infarcts, and white matter leukoaraiosis were evaluated and analyzed.
UNASSIGNED: Of 109 patients, 79 were males and 30 were females. Associated clinical comorbidities noted include hypertension (62.39%), diabetes (23.85%), and alcoholism (31.19%) apart from the history of anti-platelet/anti-coagulant usage (15.5%), previous cardiac disease (12.84%), and previous stroke/transient ischemic attacks (9.17%). Other co-existing neuroimaging abnormalities noted include cortical infarcts (27.52%), old hemorrhages (29.36%), lacunar infarcts (56.88%), and white matter leukaraiosis (67.89%).
UNASSIGNED: The clinicoradiological features of cerebral MBs in South Indian patients are similar to other Asian and Western studies with significant coexistence of clinical comorbidities and imaging features of small vessel changes. Further studies with a larger sample are needed to correlate the grade of MBs to the individual risk of these clinicoradiological characteristics.
UNASSIGNED: We studied 109 South Indian patients, who presented to a tertiary care institution for MR neuroimaging with cerebral MBs as diagnosed on MR neuroimaging based on either the gradient T2* imaging or susceptibility-weighted imaging. The clinical details and coexisting MR features of infarcts, macrohemorrhages, lacunar infarcts, and white matter leukoaraiosis were evaluated and analyzed.
UNASSIGNED: Of 109 patients, 79 were males and 30 were females. Associated clinical comorbidities noted include hypertension (62.39%), diabetes (23.85%), and alcoholism (31.19%) apart from the history of anti-platelet/anti-coagulant usage (15.5%), previous cardiac disease (12.84%), and previous stroke/transient ischemic attacks (9.17%). Other co-existing neuroimaging abnormalities noted include cortical infarcts (27.52%), old hemorrhages (29.36%), lacunar infarcts (56.88%), and white matter leukaraiosis (67.89%).
UNASSIGNED: The clinicoradiological features of cerebral MBs in South Indian patients are similar to other Asian and Western studies with significant coexistence of clinical comorbidities and imaging features of small vessel changes. Further studies with a larger sample are needed to correlate the grade of MBs to the individual risk of these clinicoradiological characteristics.
摘要：
■脑微出血（MB）最近在磁共振（MR）神经影像学上被描述为实体，被认为是小血管疾病的标志物之一。我们旨在研究在MR神经影像学中诊断出的脑MBs的临床放射学特征。
■我们研究了109名南印度患者，根据梯度T2*成像或磁敏感加权成像，在MR神经成像中诊断为脑MB，向三级护理机构进行MR神经成像。梗死的临床细节和共存的MR特征，大出血,腔隙梗死,评估和分析白质白质疏松症。
■109名患者，79名男性，30名女性。相关的临床合并症包括高血压（62.39%），糖尿病（23.85%），和酒精中毒（31.19％），除了抗血小板/抗凝剂使用史（15.5％），既往心脏病（12.84%），既往卒中/短暂性脑缺血发作（9.17%）。注意到的其他共存的神经影像学异常包括皮质梗塞（27.52％），老年出血(29.36%)，腔隙梗死(56.88%),白质白质（67.89%）。
■南印度患者的脑MBs的临床放射学特征与其他亚洲和西方研究相似，临床合并症和小血管改变的影像学特征明显并存。需要进行更大样本的进一步研究，以将MB的等级与这些临床放射学特征的个体风险相关联。
■我们研究了109名南印度患者，根据梯度T2*成像或磁敏感加权成像，在MR神经成像中诊断为脑MB，向三级护理机构进行MR神经成像。梗死的临床细节和共存的MR特征，大出血,腔隙梗死,评估和分析白质白质疏松症。
■109名患者，79名男性，30名女性。相关的临床合并症包括高血压（62.39%），糖尿病（23.85%），和酒精中毒（31.19％），除了抗血小板/抗凝剂使用史（15.5％），既往心脏病（12.84%），既往卒中/短暂性脑缺血发作（9.17%）。注意到的其他共存的神经影像学异常包括皮质梗塞（27.52％），老年出血(29.36%)，腔隙梗死(56.88%),白质白质（67.89%）。
■南印度患者的脑MBs的临床放射学特征与其他亚洲和西方研究相似，临床合并症和小血管改变的影像学特征明显并存。需要进行更大样本的进一步研究，以将MB的等级与这些临床放射学特征的个体风险相关联。
