PDF(Pubmed)
Abstract：
UNASSIGNED: Dengue virus (DENV) and Chikungunya virus (CHIKV) pose significant public health threats in Brazil, where favorable conditions facilitated the proliferation of Aedes mosquitoes. Since the mid-1980s, Brazil has experienced annual outbreaks of DENV, with recent increases in confirmed cases. In addition, CHIKV, which was first reported in 2014, has spread across the country. The concurrent presence of these viruses has triggered public health alerts in endemic regions, underscoring the complexity of managing vector-borne diseases.
UNASSIGNED: This report details a case of simultaneous DENV and CHIKV infections. A 77-year-old female patient who has diabetes and arrhythmia exhibited symptoms including fever, myalgia, and severe arthralgia. Laboratory tests confirmed the coinfection through RNA detection. The patient received supportive care, showed gradual improvement, and was eventually discharged.
UNASSIGNED: Coinfection with DENV and CHIKV cases reported here developed with mild outcomes. However, one of the patients did not recover from the arthralgia after presenting diagnostic challenges, which underscores the need for accurate differentiation to manage symptoms effectively. The reported cases, amidst increasing DENV outbreaks, highlight the urgency for preparedness in the healthcare system. The Ribeirão Preto region\'s endemicity for DENV, coupled with the rising incidence of CHIKV, emphasizes the evolving landscape of arbovirus transmission. Studies on Aedes mosquitoes suggest potential implications for human infection dynamics, warranting further investigation into arbovirus transmission efficacy and coinfection dynamics.
UNASSIGNED: This report details a case of simultaneous DENV and CHIKV infections. A 77-year-old female patient who has diabetes and arrhythmia exhibited symptoms including fever, myalgia, and severe arthralgia. Laboratory tests confirmed the coinfection through RNA detection. The patient received supportive care, showed gradual improvement, and was eventually discharged.
UNASSIGNED: Coinfection with DENV and CHIKV cases reported here developed with mild outcomes. However, one of the patients did not recover from the arthralgia after presenting diagnostic challenges, which underscores the need for accurate differentiation to manage symptoms effectively. The reported cases, amidst increasing DENV outbreaks, highlight the urgency for preparedness in the healthcare system. The Ribeirão Preto region\'s endemicity for DENV, coupled with the rising incidence of CHIKV, emphasizes the evolving landscape of arbovirus transmission. Studies on Aedes mosquitoes suggest potential implications for human infection dynamics, warranting further investigation into arbovirus transmission efficacy and coinfection dynamics.
摘要：
背景登革热病毒（DENV）和基孔肯雅病毒（CHIKV）在巴西构成了重大的公共卫生威胁，有利的条件促进了伊蚊的繁殖。自1980年代中期以来，巴西经历了每年的DENV爆发，随着最近确诊病例的增加。此外,CHIKV,这是在2014年首次报道，已经在全国范围内传播。这些病毒的同时存在引发了流行地区的公共卫生警报，强调管理媒介传播疾病的复杂性。病例介绍：本报告详述了一例同时发生DENV和CHIKV感染的病例。一名患有糖尿病和心律失常的77岁女性患者出现发烧等症状，肌痛，和严重的关节痛.实验室测试通过RNA检测证实了共感染。病人接受了支持性治疗,显示出逐步改善，最终出院了.结论本文报道的DENV和CHIKV病例合并感染，结果温和。然而,其中一名患者在出现诊断挑战后没有从关节痛中恢复过来，这强调了准确区分以有效管理症状的必要性。报告的案件，在不断增加的DENV爆发中，强调医疗系统做好准备的紧迫性。里贝朗·普雷托地区对DENV的地方性，加上CHIKV的发病率上升，强调虫媒病毒传播的演变格局。对伊蚊的研究表明，对人类感染动力学的潜在影响，保证进一步调查虫媒病毒传播效力和共感染动力学。
