PDF(Pubmed)
Abstract：
Torsion occurs as a complication in 10% of cases of ovarian tumors. It predominantly occurs in benign ones, while malignant tumors are less prone to torsion. Sertoli-Leydig cell tumors are highly unusual sex cord-stromal tumors of the ovary, accounting for less than 0.2% of all ovarian cancers. A 39-year-old patient presented to the emergency department with a Sertoli-Leydig cell tumor diagnosed due to ovarian torsion. The clinical presentation was characterized by abdominal pain. Ultrasound indicated signs of torsion, and torsion of the right ovary was subsequently confirmed during laparotomy. A salpingo-oophorectomy was performed, and histological examination revealed a moderately differentiated Sertoli-Leydig cell tumor. Sertoli-Leydig cell tumors often present with hormone-related or non-hormonal symptoms. Surgery plays a crucial role in both diagnosis and treatment. Postoperative treatment is not necessary for well-differentiated Sertoli-Leydig cell tumors in stage IA-IB. However, patients with grade 2-3 disease, advanced stage, or heterologous elements may consider adjuvant treatment. As these tumors are rare, this case contributes to the documentation of Sertoli-Leydig cell tumors, with a case diagnosed due to ovarian torsion. The case highlights the importance of establishing international registries of Sertoli-Leydig cell tumor cases for standardized management.
摘要：
在10％的卵巢肿瘤病例中，扭转是并发症。它主要发生在良性的，而恶性肿瘤不易扭转。Sertoli-Leydig细胞肿瘤是非常不寻常的卵巢性索间质肿瘤，占所有卵巢癌的不到0.2％。一名39岁的患者因卵巢扭转而被诊断为Sertoli-Leydig细胞肿瘤，被送往急诊科。临床表现以腹痛为特征。超声显示扭转迹象,随后在剖腹手术中证实了右卵巢的扭转。进行了输卵管卵巢切除术，组织学检查显示为中度分化的Sertoli-Leydig细胞肿瘤。Sertoli-Leydig细胞肿瘤通常表现为激素相关或非激素症状。手术在诊断和治疗中起着至关重要的作用。IA-IB期分化良好的Sertoli-Leydig细胞肿瘤不需要术后治疗。然而,患有2-3级疾病的患者，高级阶段,或异源元件可考虑辅助治疗。因为这些肿瘤很罕见,这个病例有助于Sertoli-Leydig细胞肿瘤的记录，诊断为卵巢扭转。该病例强调了建立Sertoli-Leydig细胞肿瘤病例国际登记册以进行标准化管理的重要性。
