PDF(Pubmed)
Abstract：
BACKGROUND Schwannomas are tumors that arise from Schwann cells that surround and support nerve cells. Most common sites for presentations are head, neck, and extremities. Schwannomas of gastrointestinal tract are rare, slow-growing tumors, usually benign, arising from gastrointestinal tract\'s neural plexus. They are histologically distinguishable from conventional schwannomas that arise in soft tissue or the central nervous system. Preoperative diagnosis of gastrointestinal schwannoma is challenging, requiring immunohistological confirmation of the nature of the tumor. Here, we report a case of 57-year-old woman with an incidental finding of an asymptomatic submucosal jejunal schwannoma. CASE REPORT A 57-year-old woman with a medical history of hematological disorder underwent a contrast abdominal computed tomography as part of medical follow-up. The imaging revealed the presence of a jejunal mass. The patient underwent laparoscopic surgical resection of the lesion, followed by side-to-side jejuno-jejunal anastomosis with 4-cm clear surgical margins. The final pathologic study revealed the presence of jejunal schwannoma, as tested positive for S-100 protein. The patient was discharged home on the fourth postoperative day, having an uneventful recovery. CONCLUSIONS Jejunal schwannoma are usually benign and asymptomatic, and they are often discovered incidentally during diagnostic tests for other conditions; therefore, it should be included in the differential diagnosis of gastrointestinal tumors. Surgical treatment appears to be necessary to achieve a definitive diagnosis through a biopsy of the tumor tissue. Benign jejunal schwannomas have a good prognosis.
摘要：
背景技术神经鞘瘤是由围绕并支持神经细胞的施万细胞产生的肿瘤。最常见的演讲地点是头部，脖子,和四肢。胃肠道神经鞘瘤是罕见的，生长缓慢的肿瘤，通常是良性的，来自胃肠道的神经丛。它们在组织学上可与软组织或中枢神经系统中出现的常规神经鞘瘤区分开。胃肠道神经鞘瘤的术前诊断具有挑战性，需要对肿瘤性质进行免疫组织学确认。这里,我们报告一例57岁女性，偶然发现无症状的粘膜下空肠神经鞘瘤。病例报告作为医学随访的一部分，一名57岁有血液病病史的妇女接受了对比腹部计算机断层扫描。成像显示存在空肠肿块。患者行腹腔镜手术切除病灶,然后是空肠-空肠侧吻合术，手术边缘清晰4厘米。最终的病理研究显示存在空肠神经鞘瘤，S-100蛋白检测呈阳性.病人在术后第四天出院回家,有一个平稳的复苏。结论空肠神经鞘瘤通常是良性和无症状的，它们通常是在其他条件的诊断测试中偶然发现的；因此，应纳入胃肠道肿瘤的鉴别诊断。手术治疗似乎是必要的，以通过对肿瘤组织进行活检来获得明确的诊断。良性空肠神经鞘瘤预后良好。
