Abstract:
In the quest for synthesizing biologically important natural products, medicinal chemists embark on an endless journey. This review focuses on the reports published towards the syntheses of diarylheptanoids, classifying them into linear, tetrahydropyran, diarylether, and biphenyl categories. The synthesis methods for each class from 2013 to 2023 are discussed, providing a comprehensive overview of the advancements in the field. Representative natural product examples are highlighted for each category. The review emphasizes the importance of diarylheptanoids in the realms of chemistry and medicine, showcasing their potential as valuable compounds for medicinal and synthetic chemists.
摘要:
在寻求合成生物重要的天然产物的过程中,药物化学家踏上了无尽的旅程。这篇综述的重点是发表的关于二芳基庚酸类化合物合成的报告,将它们分类为线性,四氢吡喃,二芳基醚,和联苯类。讨论了2013年至2023年各班的综合方法,全面概述了该领域的进展。每个类别都突出了代表性的天然产品实例。该综述强调了二芳基庚类化合物在化学和医学领域的重要性,展示它们作为有价值的化合物的潜力,为药用和合成化学家。