Abstract：
Patients with hypertensive disorders of pregnancy (HDP) are at increased risk of maternal-fetal complications and represent the third leading cause of maternal mortality. To date, it is known that women experiencing this condition during pregnancy have a higher future risk of cardiovascular events (CVD). Our objective was to report the incidence of new-onset hypertension in the postpartum period. We conducted a cohort study in high-risk pregnant patients who underwent ambulatory blood pressure monitoring (ABPM) between weeks 20-30. Patients were categorized as normotensive (NT) or gestational hypertensive (GH), excluding those with chronic hypertension, and were followed until the end of pregnancy with a postpartum assessment after 3months. Patients with HDP (39%) had a higher incidence of preeclampsia and newborns with low birth weight and preterm birth. A total of 177 pregnant women were analyzed for the primary outcome. Among those with GH, 33.3% vs 17.2% of NT (P=.014) reported new-onset hypertension. The odds ratio for developing new-onset hypertension was 2.3 (95%CI: 1.20-4.77), for those with GH. In conclusion, pregnant patients with GH assessed by ABPM between 20-30weeks are at higher risk of developing new-onset hypertension in the postpartum period, emphasizing the need for closer monitoring and control to prevent future cardiovascular complications.
摘要：
妊娠高血压疾病（HDP）患者发生母婴并发症的风险增加，是孕产妇死亡的第三大原因。迄今为止,众所周知，在怀孕期间经历这种情况的女性未来发生心血管事件（CVD）的风险更高。我们的目的是报告产后新发高血压的发生率。我们在20-30周之间接受动态血压监测（ABPM）的高危孕妇中进行了一项队列研究。患者分为血压正常（NT）或妊娠期高血压（GH），不包括慢性高血压患者,并随访至妊娠结束，3个月后进行产后评估。HDP患者（39％）的先兆子痫和低出生体重和早产的新生儿发生率较高。总共分析了177名孕妇的主要结局。在那些有GH的人中，33.3%vs17.2%的NT（P=0.014）报告新发高血压。新发高血压的比值比为2.3（95CI：1.20-4.77），对于那些有GH。总之,通过ABPM评估的20-30周GH的孕妇在产后发生新发高血压的风险较高，强调需要更密切的监测和控制，以防止未来的心血管并发症。
