Abstract:
Primary cutaneous mucinous carcinoma (PCMC) is a rare malignancy of the sweat glands that most commonly affects the periorbital area. It is characterized by slow growth over a prolonged period, and its morphology can be easily confused with a benign tumor, such as an epidermal cyst. Consequently, many patients experience recurrence after undergoing multiple resections. However, there are few reports concerning the surgical management of PCMC. We present two cases of PCMC originating in the periorbital area. The first case involved a 76-year-old man with a mass measuring 3.0× 1.5 cm that had been increasing in size. The second case was a 61-year-old man with two masses, each measuring 1.0× 1.0 cm, that were also growing. Both patients underwent wide excision with a 5-mm safety margin, which was determined based on the widest view of the cross-section of the mass on the magnetic resonance imaging. Subsequently, based on the intraoperative frozen biopsy results, both patients underwent additional excision with a 5-mm safety margin in only one direction. This report shows that, when determining the surgical margin of PCMC in periorbital area, employing imaging modalities and intraoperative frozen biopsies can be helpful for narrowing the surgical margin.
摘要:
原发性皮肤粘液性癌(PCMC)是一种罕见的汗腺恶性肿瘤,最常影响眶周区域。它的特点是长期缓慢增长,它的形态很容易与良性肿瘤混淆,如表皮囊肿。因此,许多患者在多次切除后出现复发.然而,关于PCMC的手术治疗的报道很少。我们介绍了两例起源于眶周区的PCMC。第一例涉及一名76岁的男子,体重为3.0×1.5厘米,尺寸一直在增加。第二例是一名61岁的男子,有两个肿块,每个尺寸为1.0×1.0厘米,它也在增长。两名患者均接受了5毫米安全边缘的广泛切除术,这是根据磁共振成像上肿块横截面的最宽视图确定的。随后,根据术中冷冻活检结果,两名患者仅在一个方向接受了5-mm安全裕度的额外切除.这份报告显示,在确定眶周区PCMC的手术切缘时,采用成像方式和术中冷冻活检有助于缩小手术切缘.