关键词: Delphi process allergic rhinitis allergic rhinoconjunctivitis allergy antihistamines bilastine urticaria

来  源:   DOI:10.7573/dic.2024-2-3   PDF(Pubmed)

Abstract:
UNASSIGNED: Second-generation oral H1-antihistamines, including bilastine, represent the emerging treatments of allergic rhinitis (including rhinoconjunctivitis) and chronic urticaria in both adults and children. This study analyses available evidence supporting the use of bilastine amongst second-generation antihistamines for the symptomatic treatment of allergic rhinitis and urticaria in adults and children.
UNASSIGNED: Consensus amongst experts from 17 countries on the ideal treatment of rhinitis and urticaria, and the specific role of bilastine was measured by means of a modified Delphi process. A total of 12 statements were voted on by the experts using a five-point Likert scale (1 = strongly disagree; 2 = disagree; 3 = undecided; 4 = agree; 5 = strongly agree). The definition of consensus was set at a minimum of 80% concordance for 4+5 scores (agree or strongly agree).
UNASSIGNED: All proposed statements reached consensus, with a concordance of ≥98% for five statements and ≥96% for seven.
UNASSIGNED: The wide consensus obtained for the proposed statements suggests a prominent role for bilastine in the management of allergic rhinitis and urticaria.
摘要:
第二代口服H1-抗组胺药,包括Bilastine,代表成人和儿童过敏性鼻炎(包括鼻结膜炎)和慢性荨麻疹的新兴治疗方法。这项研究分析了现有证据,支持在第二代抗组胺药中使用比拉斯汀对成人和儿童的过敏性鼻炎和荨麻疹进行对症治疗。
来自17个国家的专家就鼻炎和荨麻疹的理想治疗达成共识,并通过改进的德尔菲法测量比拉斯汀的具体作用。专家们使用五点李克特量表对总共12项声明进行了投票(1=强烈不同意;2=不同意;3=未定;4=同意;5=强烈同意)。对于4+5分数(同意或强烈同意),共识的定义设定为至少80%一致。
所有提议的声明都达成了共识,五个陈述的一致性≥98%,七个陈述的一致性≥96%。
对提议的陈述获得的广泛共识表明,比拉斯汀在过敏性鼻炎和荨麻疹的管理中具有重要作用。
公众号