Abstract：
To determine the effect of midface surgery on soft tissue changes and their relationship to hard tissue changes in patients with syndromic craniosynostosis. A retrospective analysis of patients who had undergone Le Fort III (LFIII), monobloc (MB), or facial bipartition (FB) was conducted. A 3D soft tissue mesh was generated from the preoperative scan and registered to the postoperative scan, after which the advancement was visualised. A total of 68 patients were included: 28 had undergone LFIII, 27 MB, and 13 FB. The included diagnoses were Apert (n = 23), Crouzon (n = 34), and craniofrontonasal syndrome (n = 11). After LFIII, most soft tissue advancement was seen around subnasale and pronasale (mean 15.1 ± 5.9 mm and 14.7 ± 5.7 mm, at age 7-12 years). After MB, a greater hard tissue than soft tissue advancement was seen for most landmarks, showing a high positive correlation. In patients undergoing FB without distraction (n = 10), mean preoperative inter-canthal distance was 48.9 mm, this reduced by 6.9 mm postoperatively. This study provides a comprehensive overview of the outcomes after midface surgery using 3D quantification for a better understanding of the soft tissue changes and their relationship to hard tissue changes.
摘要：
目的探讨面中手术对综合征性颅骨滑脱症患者软组织改变的影响及其与硬组织改变的关系。接受LeFortIII（LFII）治疗的患者的回顾性分析，单块(MB),或进行面部二分置(FB)。根据术前扫描生成3D软组织网格，并将其注册到术后扫描中，之后，进步被可视化了。共包括68例患者：28例接受LFII，27MB,13FB纳入的诊断为Apert(n=23)，克鲁松（n=34），和颅额鼻综合征（n=11）。在LFII之后,大部分软组织前移见于鼻下和鼻突周围(平均15.1±5.9mm和14.7±5.7mm,7-12岁)。MB之后,一个更大的硬组织比软组织的进步是在大多数标志，呈高度正相关。在不分心的FB患者中（n=10），术前平均咽间距离为48.9mm,术后减少6.9毫米。为了更好地了解软组织变化及其与硬组织变化的关系，本研究使用3D定量提供了中脸手术后结果的全面概述。
