Abstract：
Due to their relatively high prevalence and commensalism, the pathogenicity of Demodex mites has been debated. Recent data, however, show Demodex to be associated with skin and ocular surface diseases such as rosacea, blepharitis, and keratitis. Here the authors report the first known case, to the best of the their knowledge, of Demodex infestation mimicking preseptal cellulitis in an adult human. A 29-year-old male bilaterally blind from advanced retinopathy of prematurity presented with a 2-month history of right-greater-than-left upper eyelid and periocular/cheek swelling, redness, and ocular discharge that did not resolve with oral antibiotics or oral steroids. Based on MRI findings, biopsies of the right lacrimal gland, right orbital fat, and right upper eyelid preseptal skin were obtained which revealed marked intrafollicular Demodex mite density and budding yeasts in the upper eyelid skin. This case serves to alert clinicians to this entity that may not otherwise be usually considered in ophthalmic clinical practice.
摘要：
由于它们相对较高的流行率和共生主义，蠕形螨的致病性一直存在争议。最近的数据,然而,显示蠕形螨与皮肤和眼表疾病如酒渣鼻有关，眼睑炎,和角膜炎。作者在这里报告了第一个已知的病例，据他们所知，模仿成年人脑前蜂窝织炎的蠕形螨感染。一名29岁的男性因早产儿晚期视网膜病变而双侧失明，有2个月的右上眼睑大于左和眼周/脸颊肿胀病史，发红,以及口服抗生素或口服类固醇未解决的眼部分泌物。根据MRI检查结果,右侧泪腺活检,右眶脂肪,获得右上眼睑前皮肤，显示上眼睑皮肤中有明显的滤泡内蠕形螨螨密度和出芽酵母。这种情况用于提醒临床医生注意该实体，否则在眼科临床实践中通常不会考虑该实体。
