关键词: buspirone delayed ejaculation erectile dysfunction generalised anxiety disorder psychiatry selective serotonin reuptake inhibitor sexual dysfunction side effects

来  源:   DOI:10.7759/cureus.57981   PDF(Pubmed)

Abstract:
Sexual dysfunction is a common problem for patients taking antidepressants, with the highest prevalence rates observed with selective serotonin reuptake inhibitors (SSRIs). Sexual dysfunction can be distressing for patients and may lead to medication non-adherence; thus, it is important for the prescribers to be aware of the available treatment strategies, as well as of the strength of the evidence that supports their use. We present the case of a patient who developed delayed ejaculation after the initiation of sertraline for the treatment of depression. The patient\'s sexual dysfunction resolved after the addition of buspirone. A discussion of this case is followed by a review of the existing literature examining the possible role of buspirone in the treatment of SSRI-induced sexual dysfunction.
摘要:
性功能障碍是服用抗抑郁药的患者的常见问题,选择性5-羟色胺再摄取抑制剂(SSRIs)的患病率最高。性功能障碍可能会困扰患者,并可能导致药物不依从性;因此,重要的是处方者要了解可用的治疗策略,以及支持其使用的证据的强度。我们介绍了一例患者在开始使用舍曲林治疗抑郁症后出现射精延迟的情况。添加丁螺环酮后,患者的性功能障碍得以缓解。对这种情况进行讨论后,对现有文献进行综述,以探讨丁螺环酮在治疗SSRI引起的性功能障碍中的可能作用。
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