PDF(Pubmed)
Abstract：
UNASSIGNED: Fetal ultrasound has limitations, especially if the patient is obese or in cases with oligohydramnios. Magnetic resonance imaging (MRI) can then be used as a complement, but only few studies have focused on examinations in the second trimester.
UNASSIGNED: To validate MRI as a complement to diagnose fetal anomalies in the second trimester.
UNASSIGNED: This retrospective study retrieved data from January 2008 to July 2012 from the Fetal Medicine Unit and Department of Radiology at Uppsala University Hospital. Ultrasound and MRI findings were reviewed in 121 fetuses in relation to the final diagnosis, including postpartum follow-up and autopsy results.
UNASSIGNED: Of the 121 fetuses, 51 (42%) had a CNS anomaly and 70 (58%) a non-CNS anomaly diagnosed or suspected. MRI provided additional information in 21% of all cases without changing the management and revealed information that changed the management of the pregnancy in 13%. When a CNS anomaly was detected or suspected, the MRI provided additional information in 22% and changed the management in 10%. The corresponding figures for non-CNS cases were 21% and 16%, respectively. The proportion of cases with additional information that changed the management was especially high in patients with a BMI >30 kg/m2 (25%) and in patients with oligohydramnios (38%). In five cases in category III, false-positive ultrasound findings were identified.
UNASSIGNED: MRI in the second trimester complements ultrasound and improves diagnosis of fetal CNS- and non-CNS anomalies especially when oligohydramnios or maternal obesity is present.
UNASSIGNED: To validate MRI as a complement to diagnose fetal anomalies in the second trimester.
UNASSIGNED: This retrospective study retrieved data from January 2008 to July 2012 from the Fetal Medicine Unit and Department of Radiology at Uppsala University Hospital. Ultrasound and MRI findings were reviewed in 121 fetuses in relation to the final diagnosis, including postpartum follow-up and autopsy results.
UNASSIGNED: Of the 121 fetuses, 51 (42%) had a CNS anomaly and 70 (58%) a non-CNS anomaly diagnosed or suspected. MRI provided additional information in 21% of all cases without changing the management and revealed information that changed the management of the pregnancy in 13%. When a CNS anomaly was detected or suspected, the MRI provided additional information in 22% and changed the management in 10%. The corresponding figures for non-CNS cases were 21% and 16%, respectively. The proportion of cases with additional information that changed the management was especially high in patients with a BMI >30 kg/m2 (25%) and in patients with oligohydramnios (38%). In five cases in category III, false-positive ultrasound findings were identified.
UNASSIGNED: MRI in the second trimester complements ultrasound and improves diagnosis of fetal CNS- and non-CNS anomalies especially when oligohydramnios or maternal obesity is present.
摘要：
■胎儿超声有局限性，特别是如果患者肥胖或羊水过少。然后可以使用磁共振成像（MRI）作为补充，但是只有少数研究集中在妊娠中期的检查上。
■验证MRI作为诊断孕中期胎儿畸形的补充。
这项回顾性研究从2008年1月至2012年7月从乌普萨拉大学医院的胎儿医学部门和放射科检索了数据。对121例胎儿的超声和MRI检查结果与最终诊断有关，包括产后随访和尸检结果。
■在121个胎儿中，51（42％）患有CNS异常，70（58％）被诊断或怀疑为非CNS异常。MRI在所有病例的21％中提供了额外的信息，而没有改变管理，并在13％中揭示了改变妊娠管理的信息。当检测到或怀疑CNS异常时，MRI提供了22%的额外信息,改变了10%的管理.非中枢神经系统病例的相应数字分别为21%和16%,分别。在BMI>30kg/m2（25％）和羊水过少（38％）的患者中，具有其他信息改变管理的病例比例尤其高。在三类的五个案件中，确定了假阳性超声检查结果。
■妊娠中期的MRI补充了超声检查，并改善了胎儿CNS和非CNS异常的诊断，尤其是在羊水过少或孕妇肥胖时。
■验证MRI作为诊断孕中期胎儿畸形的补充。
这项回顾性研究从2008年1月至2012年7月从乌普萨拉大学医院的胎儿医学部门和放射科检索了数据。对121例胎儿的超声和MRI检查结果与最终诊断有关，包括产后随访和尸检结果。
■在121个胎儿中，51（42％）患有CNS异常，70（58％）被诊断或怀疑为非CNS异常。MRI在所有病例的21％中提供了额外的信息，而没有改变管理，并在13％中揭示了改变妊娠管理的信息。当检测到或怀疑CNS异常时，MRI提供了22%的额外信息,改变了10%的管理.非中枢神经系统病例的相应数字分别为21%和16%,分别。在BMI>30kg/m2（25％）和羊水过少（38％）的患者中，具有其他信息改变管理的病例比例尤其高。在三类的五个案件中，确定了假阳性超声检查结果。
■妊娠中期的MRI补充了超声检查，并改善了胎儿CNS和非CNS异常的诊断，尤其是在羊水过少或孕妇肥胖时。
