关键词: Acute schistosomiasis Case report Katayama syndrome Schistosomiasis Swimmer’s itch

来  源:   DOI:10.1016/j.rmcr.2024.102032   PDF(Pubmed)

Abstract:
UNASSIGNED: Katayama syndrome is an acute manifestation of schistosomiasis, a parasitic infection that manifests itself through a hypersensitivity reaction to migrating larvae and early egg deposition. Left undiagnosed and untreated, acute schistosomiasis can develop into chronic schistosomiasis which can lead to debilitating morbidity such as pulmonary hypertension. This case highlights that Katayama syndrome can also been seen in regions where the parasite is not endemic, as it occurs in travelers returning from endemic regions or in immigrants.
UNASSIGNED: We describe the case of a 26-year-old asthmatic male, who presented with systemic symptoms including fever, myalgia, night sweats as well as gastro-intestinal and pulmonary complaints since five days. At presentation, there was a raised blood eosinophil count and nodular lesions were seen on computed tomography. After considering diagnoses such as tuberculosis, vasculitis and hypereosinophilic syndrome, it was repeated history taking that revealed that the patient had suffered from swimmer\'s itch during a stay in Guinea. A stool sample showed microscopic presence of Schistosoma mansoni eggs, confirming the diagnosis of Katayama syndrome. The patient was treated with tapered corticosteroids to suppress the hypersensitivity reaction and praziquantel was added to cure the parasitic infection. This led to a complete resolution of the patients\' symptoms and radiological abnormalities. Negative stool samples confirmed the eradication of the schistosomes.
UNASSIGNED: Swimmer\'s itch and Katayama syndrome are manifestations of acute schistosomiasis. It is important to recognize the syndrome, because early diagnosis and adequate treatment can prevent chronic disease and significant morbidity.
摘要:
片山综合征是血吸虫病的急性表现,寄生虫感染,通过对迁移幼虫和早期卵沉积的超敏反应而表现出来。未经诊断和治疗,急性血吸虫病可发展为慢性血吸虫病,可导致肺动脉高压等衰弱性疾病。这个病例突出表明,片山综合征也可以在寄生虫不流行的地区看到,因为它发生在从流行地区返回的旅行者或移民中。
我们描述了一个26岁的哮喘男性,出现全身症状包括发烧,肌痛,自五天以来,盗汗以及胃肠道和肺部不适。在介绍时,血液嗜酸性粒细胞计数升高,计算机断层扫描发现结节性病变.在考虑结核病等诊断后,血管炎和嗜酸性粒细胞增多综合征,反复的历史记录显示患者在几内亚逗留期间患有游泳者的瘙痒。粪便样本显示显微镜下存在曼氏血吸虫卵,确认Katayama综合征的诊断。患者接受锥形皮质类固醇治疗以抑制超敏反应,并加入吡喹酮治疗寄生虫感染。这导致完全缓解患者的症状和放射学异常。阴性粪便样本证实了血吸虫的根除。
游泳瘙痒和片山综合征是急性血吸虫病的表现。认识到这种综合症很重要,因为早期诊断和适当的治疗可以预防慢性疾病和显著的发病率。
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