PDF(Pubmed)
Abstract：
UNASSIGNED: The reasons for gastrointestinal bleeding among patients with acquired immune deficiency syndrome (AIDS) were complex. Here we present an unusual case of life-threatening gastrointestinal bleeding caused by a cytomegalovirus-induced duodenal ulcer in an AIDS patient.
UNASSIGNED: A 31-year-old male with AIDS was admitted on July 18, 2023, complaining of abdominal pain for 38 days and intermittent hematochezia for 12 days. During his hospitalization, gastrointestinal endoscopy attributed gastrointestinal bleeding to a giant duodenal ulcer. Furthermore, cytomegalovirus(CMV) infection was confirmed as the reason for the ulcer through metagenomic next-generation sequencing (mNGs), hematoxylin-eosin(HE) staining, and immunohistochemistry (IHC) staining for the biopsy tissue. The patient\'s gastrointestinal bleeding was stopped by interventional embolization. Following a 4-week course of anti-CMV treatment, the giant duodenal ulcer was cured.
UNASSIGNED: For AIDS patients with gastrointestinal bleeding, the CMV-induced gastrointestinal ulcer should be considered. Comprehensive mothods (mNGs, HE staining and IHC staining for biopsy tissue) were benefit for confirmed diagnosis. Beside anti-CMV treatment, the interventional embolization is a choice for hemostasis.
UNASSIGNED: A 31-year-old male with AIDS was admitted on July 18, 2023, complaining of abdominal pain for 38 days and intermittent hematochezia for 12 days. During his hospitalization, gastrointestinal endoscopy attributed gastrointestinal bleeding to a giant duodenal ulcer. Furthermore, cytomegalovirus(CMV) infection was confirmed as the reason for the ulcer through metagenomic next-generation sequencing (mNGs), hematoxylin-eosin(HE) staining, and immunohistochemistry (IHC) staining for the biopsy tissue. The patient\'s gastrointestinal bleeding was stopped by interventional embolization. Following a 4-week course of anti-CMV treatment, the giant duodenal ulcer was cured.
UNASSIGNED: For AIDS patients with gastrointestinal bleeding, the CMV-induced gastrointestinal ulcer should be considered. Comprehensive mothods (mNGs, HE staining and IHC staining for biopsy tissue) were benefit for confirmed diagnosis. Beside anti-CMV treatment, the interventional embolization is a choice for hemostasis.
摘要：
■获得性免疫缺陷综合征（AIDS）患者消化道出血的原因复杂。在这里，我们介绍了一例由巨细胞病毒引起的AIDS患者十二指肠溃疡引起的危及生命的胃肠道出血的罕见病例。
■一名31岁的男性艾滋病患者于2023年7月18日入院，主诉腹痛38天，间歇性便血12天。在他住院期间,胃肠内镜将消化道出血归因于巨大的十二指肠溃疡。此外，巨细胞病毒（CMV）感染通过宏基因组下一代测序（mNG）证实为溃疡的原因，苏木精-伊红（HE）染色，和活检组织的免疫组织化学（IHC）染色。患者的消化道出血通过介入栓塞停止。经过4周的抗CMV治疗，巨大的十二指肠溃疡被治愈了.
■对于患有消化道出血的艾滋病患者，应考虑CMV引起的胃肠道溃疡。综合方法(mNG，活检组织的HE染色和IHC染色）有利于确诊。除了抗CMV治疗，介入栓塞是止血的一种选择。
■一名31岁的男性艾滋病患者于2023年7月18日入院，主诉腹痛38天，间歇性便血12天。在他住院期间,胃肠内镜将消化道出血归因于巨大的十二指肠溃疡。此外，巨细胞病毒（CMV）感染通过宏基因组下一代测序（mNG）证实为溃疡的原因，苏木精-伊红（HE）染色，和活检组织的免疫组织化学（IHC）染色。患者的消化道出血通过介入栓塞停止。经过4周的抗CMV治疗，巨大的十二指肠溃疡被治愈了.
■对于患有消化道出血的艾滋病患者，应考虑CMV引起的胃肠道溃疡。综合方法(mNG，活检组织的HE染色和IHC染色）有利于确诊。除了抗CMV治疗，介入栓塞是止血的一种选择。
