PDF(Pubmed)
Abstract：
UNASSIGNED: Hypothyroidism is the result of impaired production and secretion of thyroid hormones. The cardiovascular system is affected by fluctuations in thyroid hormone levels. Stressful events or stressors can affect the hypothalamic-pituitary-thyroid (HPT) axis and psychological and physiological responses. Stress increases thyroid hormone levels while decreasing TSH levels, which exacerbates autoimmune thyroid disease.
UNASSIGNED: To evaluate the relationship between stress and primary hypothyroidism.
UNASSIGNED: A total of 77 newly diagnosed hypothyroid patients (TSH >5.0 mIU/L) and 77 healthy adults (TSH 0.5-5.0 mIU/L) were enrolled. During a brief general physical examination, the following values were measured: height, weight, blood pressure, pulse, and pulse rate. A brief systemic examination of the cardiovascular system and lungs was also performed to rule out systemic diseases. Heart rate variability (HRV) processing and analysis were performed using Pro LabChart (PowerLab 8Pro) data analysis software from AD Instrument.
UNASSIGNED: Mean Avg. RR was significantly higher, RM SSD and pRR50 were significantly lower in cases than in controls. Mean HF was significantly lower and LF/HF (frequency range) was significantly higher in cases than in controls. Mean PSS was significantly higher in cases (25.82 ± 2.83) than in controls (22.47 ± 2.10). The majority of cases (54.5%) had a high stress level. The TSH level showed a highly significant correlation with the LF/HF ratio and with the PSS score.
UNASSIGNED: The mean Avg. RR and HF were significantly higher, RM SSD and pRR50 and LF/HF (frequency range) were significantly lower in hypothyroid patients.
UNASSIGNED: To evaluate the relationship between stress and primary hypothyroidism.
UNASSIGNED: A total of 77 newly diagnosed hypothyroid patients (TSH >5.0 mIU/L) and 77 healthy adults (TSH 0.5-5.0 mIU/L) were enrolled. During a brief general physical examination, the following values were measured: height, weight, blood pressure, pulse, and pulse rate. A brief systemic examination of the cardiovascular system and lungs was also performed to rule out systemic diseases. Heart rate variability (HRV) processing and analysis were performed using Pro LabChart (PowerLab 8Pro) data analysis software from AD Instrument.
UNASSIGNED: Mean Avg. RR was significantly higher, RM SSD and pRR50 were significantly lower in cases than in controls. Mean HF was significantly lower and LF/HF (frequency range) was significantly higher in cases than in controls. Mean PSS was significantly higher in cases (25.82 ± 2.83) than in controls (22.47 ± 2.10). The majority of cases (54.5%) had a high stress level. The TSH level showed a highly significant correlation with the LF/HF ratio and with the PSS score.
UNASSIGNED: The mean Avg. RR and HF were significantly higher, RM SSD and pRR50 and LF/HF (frequency range) were significantly lower in hypothyroid patients.
摘要：
■甲状腺功能减退是甲状腺激素产生和分泌受损的结果。心血管系统受到甲状腺激素水平波动的影响。应激事件或应激源可影响下丘脑-垂体-甲状腺（HPT）轴以及心理和生理反应。应激增加甲状腺激素水平，同时降低TSH水平，这加剧了自身免疫性甲状腺疾病。
■评估压力与原发性甲状腺功能减退症之间的关系。
■共纳入77例新诊断甲状腺功能减退患者(TSH>5.0mIU/L)和77例健康成年人(TSH0.5-5.0mIU/L)。在简短的一般体检中，测量了以下值：高度，体重,血压,脉搏,和脉搏率。还对心血管系统和肺进行了简短的全身性检查，以排除全身性疾病。使用来自ADInstrument的ProLabChart(PowerLab8Pro)数据分析软件进行心率变异性(HRV)处理和分析。
■平均值。RR明显较高，病例的RMSSD和pRR50明显低于对照组。与对照组相比，平均HF显着降低，而LF/HF（频率范围）显着升高。病例的平均PSS（25.82±2.83）明显高于对照组（22.47±2.10）。大多数病例（54.5％）具有较高的压力水平。TSH水平与LF/HF比率和PSS评分高度显着相关。
■平均值。RR和HF显著升高，甲状腺功能减退患者的RMSSD和pRR50和LF/HF（频率范围）显着降低。
■评估压力与原发性甲状腺功能减退症之间的关系。
■共纳入77例新诊断甲状腺功能减退患者(TSH>5.0mIU/L)和77例健康成年人(TSH0.5-5.0mIU/L)。在简短的一般体检中，测量了以下值：高度，体重,血压,脉搏,和脉搏率。还对心血管系统和肺进行了简短的全身性检查，以排除全身性疾病。使用来自ADInstrument的ProLabChart(PowerLab8Pro)数据分析软件进行心率变异性(HRV)处理和分析。
■平均值。RR明显较高，病例的RMSSD和pRR50明显低于对照组。与对照组相比，平均HF显着降低，而LF/HF（频率范围）显着升高。病例的平均PSS（25.82±2.83）明显高于对照组（22.47±2.10）。大多数病例（54.5％）具有较高的压力水平。TSH水平与LF/HF比率和PSS评分高度显着相关。
■平均值。RR和HF显著升高，甲状腺功能减退患者的RMSSD和pRR50和LF/HF（频率范围）显着降低。
