PDF(Pubmed)
Abstract：
UNASSIGNED: Tobacco contains harmful carcinogens that have been associated with cancers. Some studies have associated tobacco smoking with prostate cancer (PCa). The relationship between alcohol consumption as a risk factor for prostate cancer has been debated. Some studies associated alcohol consumption with increased risk of PCa, associating alcohol consumption with higher-grade cancers and poorer prognosis. Other studies have found a minimal relationship with PCa, with some even suggesting that alcohol consumption may even be protective. This study evaluates the association between smoking and alcohol consumption in prostate cancer patients.
UNASSIGNED: This is a retrospective study on one hundred and fifty-two patients diagnosed with prostate cancer with a known history of both smoking and or alcohol consumption managed over a 9year period from January 2012 to December 2020 from three Urology referrals hospitals. Patients with incomplete history were excluded. Their data such as age, a history of cigarette smoking, prostate-specific antigen level, prostate biopsy histopathology reports, and Gleason\'s grade were extracted. This was coded into Microsoft Excel and analyzed with SPSS version 20. The results were analyzed and presented in tables and charts.
UNASSIGNED: One hundred and thirty-five patients had a premorbid history of smoking and alcohol consumption with a mean age of 69 years and a modal age in the 70-79-year age group. Fifty-three (39.3%) of the patients had a history of cigarette smoking, ninety-four (69.6%) had a history of alcohol consumption. In comparison, fifty-one (37.8%) had a history of cigarette smoking and alcohol consumption. The high-risk Gleason\'s 8-10 prostate cancer was commoner among smokers than nonsmokers. There was no statistically significant association between cigarette smoking and alcohol consumption alone and combined with PCa.
UNASSIGNED: The high-risk Gleason\'s 8-10 prostate cancer was commoner among smokers than nonsmokers. There was no statistically significant association between cigarette smoking and alcohol consumption and the risk of prostate cancer.
UNASSIGNED: This is a retrospective study on one hundred and fifty-two patients diagnosed with prostate cancer with a known history of both smoking and or alcohol consumption managed over a 9year period from January 2012 to December 2020 from three Urology referrals hospitals. Patients with incomplete history were excluded. Their data such as age, a history of cigarette smoking, prostate-specific antigen level, prostate biopsy histopathology reports, and Gleason\'s grade were extracted. This was coded into Microsoft Excel and analyzed with SPSS version 20. The results were analyzed and presented in tables and charts.
UNASSIGNED: One hundred and thirty-five patients had a premorbid history of smoking and alcohol consumption with a mean age of 69 years and a modal age in the 70-79-year age group. Fifty-three (39.3%) of the patients had a history of cigarette smoking, ninety-four (69.6%) had a history of alcohol consumption. In comparison, fifty-one (37.8%) had a history of cigarette smoking and alcohol consumption. The high-risk Gleason\'s 8-10 prostate cancer was commoner among smokers than nonsmokers. There was no statistically significant association between cigarette smoking and alcohol consumption alone and combined with PCa.
UNASSIGNED: The high-risk Gleason\'s 8-10 prostate cancer was commoner among smokers than nonsmokers. There was no statistically significant association between cigarette smoking and alcohol consumption and the risk of prostate cancer.
摘要：
■烟草含有与癌症有关的有害致癌物。一些研究将吸烟与前列腺癌（PCa）联系起来。饮酒作为前列腺癌的危险因素之间的关系一直存在争议。一些研究表明饮酒与PCa风险增加有关，饮酒与更高级别的癌症和更差的预后相关。其他研究发现与PCa的关系很小，有些人甚至暗示饮酒甚至可能是保护性的。这项研究评估了前列腺癌患者吸烟与饮酒之间的关系。
■这是一项回顾性研究，研究对象是2012年1月至2020年12月在三家泌尿外科转诊医院进行了9年的已知吸烟和饮酒史的一百五十二例前列腺癌患者。不完全病史的患者被排除在外。他们的数据，如年龄，有吸烟史,前列腺特异性抗原水平,前列腺活检组织病理学报告，和格里森的等级被提取。这被编码到MicrosoftExcel中，并用SPSS版本20进行分析。对结果进行了分析，并在表格和图表中呈现。
■150名患者有吸烟和饮酒的前病史，平均年龄为69岁，70-79岁年龄组为模态年龄。53例（39.3%）患者有吸烟史，94（69.6％）有饮酒史。相比之下,51人(37.8%)有吸烟和饮酒史.高风险Gleason的8-10前列腺癌在吸烟者中比非吸烟者更常见。单独吸烟和饮酒以及与PCa联合使用之间没有统计学上的显着关联。
■高风险Gleason的8-10前列腺癌在吸烟者中比非吸烟者更常见。吸烟和饮酒与前列腺癌风险之间没有统计学上的显着关联。
■这是一项回顾性研究，研究对象是2012年1月至2020年12月在三家泌尿外科转诊医院进行了9年的已知吸烟和饮酒史的一百五十二例前列腺癌患者。不完全病史的患者被排除在外。他们的数据，如年龄，有吸烟史,前列腺特异性抗原水平,前列腺活检组织病理学报告，和格里森的等级被提取。这被编码到MicrosoftExcel中，并用SPSS版本20进行分析。对结果进行了分析，并在表格和图表中呈现。
■150名患者有吸烟和饮酒的前病史，平均年龄为69岁，70-79岁年龄组为模态年龄。53例（39.3%）患者有吸烟史，94（69.6％）有饮酒史。相比之下,51人(37.8%)有吸烟和饮酒史.高风险Gleason的8-10前列腺癌在吸烟者中比非吸烟者更常见。单独吸烟和饮酒以及与PCa联合使用之间没有统计学上的显着关联。
■高风险Gleason的8-10前列腺癌在吸烟者中比非吸烟者更常见。吸烟和饮酒与前列腺癌风险之间没有统计学上的显着关联。
