Abstract：
Pseudoalteromonas sp. CuT4-3, a copper resistant bacterium, was isolated from deep-sea hydrothermal sulfides on the Southwest Indian Ridge (SWIR), is an aerobic, mesophilic and rod-shaped bacterium belonging to the family Pseudoalteromonadaceae (class Gammaproteobacteria, order Alteromonadales). In this study, we present the complete genome sequence of strain CuT4-3, which consists of a single circular chromosome comprising 3,660,538 nucleotides with 41.05% G + C content and two circular plasmids comprising 792,064 nucleotides with 40.36% G + C content and 65,436 nucleotides with 41.50% G + C content. In total, 4078 protein coding genes, 105 tRNA genes, and 25 rRNA genes were obtained. Genomic analysis of strain CuT4-3 identified numerous genes related to heavy metal resistance (especially copper) and EPS production. The genome of strain CuT4-3 will be helpful for further understanding of its adaptive strategies, particularly its ability to resist heavy metal, in the deep-sea hydrothermal vent environment.
摘要：
假交替单胞菌属。CuT4-3，一种铜抗性细菌，从西南印度脊（SWIR）的深海热液硫化物中分离出来，是一种有氧运动，嗜温和杆状细菌，属于假变形杆菌科（伽玛变形杆菌，订购Alteromonadales）。在这项研究中,我们提供了CuT4-3菌株的完整基因组序列，该序列由一个包含3,660,538个核苷酸的单个环状染色体和两个包含792,064个核苷酸的GC含量为40.36％的环状质粒和65,436个核苷酸的GC含量为41.50％的环状质粒组成。总的来说,4078个蛋白质编码基因,105个tRNA基因，并获得25个rRNA基因。菌株CuT4-3的基因组分析鉴定了许多与重金属抗性(尤其是铜)和EPS产生相关的基因。菌株CuT4-3的基因组将有助于进一步了解其适应策略，特别是它抵抗重金属的能力，在深海热液喷口环境中。
