关键词: Cerebral phaeohyphomycosis Dematiaceous fungi Rhinocladiella mackenziei

Mesh : Humans Male Adult Brain Abscess / microbiology diagnosis drug therapy Antifungal Agents / therapeutic use Cerebral Phaeohyphomycosis / diagnosis microbiology India Thalamus / pathology microbiology diagnostic imaging Treatment Outcome

来  源:   DOI:10.1016/j.ijmmb.2024.100605

Abstract:
Cerebral phaeohyphomycosis (CP) stands as an exceedingly uncommon yet severe type of fungal infection affecting the central nervous system, attributable to dematiaceous fungi. Despite the patient\'s immune status, CP is associated with grave prognosis. In the present study, authors describe the first case of left thalamic fungal abscess due to Rhinocladiella mackenziei in an immunocompetent 39-year-old male patient in Jaipur, Rajasthan. Early diagnosis by direct microscopy of aspirated pus and extensive management with surgical excision and prolonged antifungal coverage showed favourable outcome. The present case is one of the few cases documented globally who has survived.
摘要:
脑性真菌病(CP)是一种非常罕见但严重的真菌感染类型,会影响中枢神经系统。可归因于致命性真菌。尽管病人的免疫状态,CP与严重预后相关。在本研究中,作者描述了在斋浦尔的一名免疫功能正常的39岁男性患者中,由于麦肯齐莱氏菌引起的第一例左丘脑真菌脓肿,拉贾斯坦邦.通过直接显微镜检查抽吸脓液的早期诊断以及手术切除和长期抗真菌覆盖的广泛治疗显示出有利的结果。本案是全球记录的少数幸存病例之一。
公众号