Janus 激酶 1 对胰腺癌的发生和发展至关重要。
关键词: CEBPD CP: Cancer Janus kinase 1 PDAC RNA sequencing STAT proteins gene targeting humans mice pancreatic cancer pancreatic neoplasms phosphorylation signal transduction transcription factor transgenic tyrosine kinase
Mesh : Animals Janus Kinase 1 / metabolism genetics Pancreatic Neoplasms / pathology genetics metabolism Humans Mice Carcinoma, Pancreatic Ductal / pathology genetics metabolism STAT3 Transcription Factor / metabolism CCAAT-Enhancer-Binding Protein-delta / metabolism genetics Disease Progression Signal Transduction Cell Line, Tumor Mice, Knockout
来 源:
DOI:10.1016/j.celrep.2024.114202
PDF(Pubmed)